As titanium dioxide (TiO2) nanoparticles are widely used commercially, their potential
biosafety and metabolic mechanism needs to be fully explained. In this study, the cytotoxicity …

In this paper, we present an optimized procedure for metabolomic analysis of endogenous
metabolites in mouse fibroblast (L929) cell line using gas chromatography/time-of-flight …

Titanium dioxide nanoparticles (nano-TiO2) have been widely applied in daily life and
subsequent problem on the potential health risk are raised. Studies on the toxicity of nano …

Abstract Food grade TiO 2 (E171) is a synthetic additive, and widely used as a coloring
agent in many foods, pharmaceutical and personal care products. A few reports have …

Titanium dioxide (TiO 2) is a common additive in many foods, pigments, personal care
products, and other consumer products used in daily life. Despite the widespread use of …

Until now, a few studies have been conducted on the destructive effects of TiO2 NPs in living
organisms, and studies on the toxicity of TiO2 NPs are still in the beginning phases …

Nanotitanium dioxide (TiO2) is an important industrial material that is widely used as an
additive in cosmetics, pharmaceuticals, and food colorants. Although the small size of the …

As titanium dioxide nanoparticles (TiO 2 NPs) are widely used commercially, their potential
toxicity on human health has attracted particular attention. In the present study, the oral …

With large-scale production and wide application of nano-titanium oxide (TiO2), its health
hazard has attracted extensive attention worldwide. In this study, mouse macrophages (Ana …

Background Due to its excellent physicochemical properties and wide applications in
consumer goods, titanium dioxide nanoparticles (TiO 2 NPs) have been increasingly …