Allergen1 regulates polysaccharide structure in Cryptococcus neoformans

N Jain, RJB Cordero, A Casadevall… - Molecular …, 2013 - Wiley Online Library
C ryptococcus neoformans is an important human, fungal pathogen that sheds
polysaccharide (exo‐PS) into host tissues. While shed exo‐PS mediates numerous …

ALL2, a Homologue of ALL1, Has a Distinct Role in Regulating pH Homeostasis in the Pathogen Cryptococcus neoformans

N Jain, T Bouklas, A Gupta, AK Varshney… - Infection and …, 2016 - Am Soc Microbiol
Cryptococcus neoformans is a facultative intracellular fungal pathogen that has a
polysaccharide capsule and causes life-threatening meningoencephalitis. Its capsule, as …

The endosomal sorting complex required for transport machinery influences haem uptake and capsule elaboration in Cryptococcus neoformans

G Hu, M Caza, B Cadieux, E Bakkeren… - Molecular …, 2015 - Wiley Online Library
Iron availability is a key determinant of virulence in the pathogenic fungus C ryptococcus
neoformans. Previous work revealed that the ESCRT (endosomal sorting complex required …

The iron-and cAMP-regulated gene SIT1 influences ferrioxamine B utilization, melanization and cell wall structure in Cryptococcus neoformans

KL Tangen, WH Jung, AP Sham, T Lian… - …, 2007 - microbiologyresearch.org
The mechanisms by which pathogens sense and transport iron are important during
infection, because of the low availability of free iron in the mammalian host. Iron is a key …

[HTML][HTML] HapX Positively and Negatively Regulates the Transcriptional Response to Iron Deprivation in Cryptococcus neoformans

WH Jung, S Saikia, G Hu, J Wang, CKY Fung… - PLoS …, 2010 - journals.plos.org
The fungal pathogen Cryptococcus neoformans is a major cause of illness in
immunocompromised individuals such as AIDS patients. The ability of the fungus to acquire …

[HTML][HTML] Transcriptional Profiling of Bacillus anthracis Sterne (34F2) during Iron Starvation

PE Carlson Jr, KA Carr, BK Janes, EC Anderson… - PLoS …, 2009 - journals.plos.org
Lack of available iron is one of many environmental challenges that a bacterium encounters
during infection and adaptation to iron starvation is important for the pathogen to efficiently …

Cryptococcus interactions with macrophages: evasion and manipulation of the phagosome by a fungal pathogen

SA Johnston, RC May - Cellular microbiology, 2013 - Wiley Online Library
C ryptococcus is a potentially fatal fungal pathogen and a leading cause of death in
immunocompromised patients. As an opportunistic and facultative intracellular pathogen of …

[HTML][HTML] A Role for LHC1 in Higher Order Structure and Complement Binding of the Cryptococcus neoformans Capsule

YD Park, S Shin, J Panepinto, J Ramos, J Qiu… - PLoS …, 2014 - journals.plos.org
Polysaccharide capsules are important virulence factors for many microbial pathogens
including the opportunistic fungus Cryptococcus neoformans. In the present study, we …

The Streptococcus mutans Rhamnose-glucose Polysaccharide Plays an Important Role in Oxidative Stress Resistance and Iron Homeostasis

AP Bischer, RC Faustoferri, CJ Kovacs, SR Gill… - bioRxiv, 2022 - biorxiv.org
The rhamnose-glucose polysaccharide (RGP) of Streptococcus mutans is known to play an
essential role in cell division and biofilm formation. It has become increasingly apparent that …

Role of glucose in the expression of Cryptococcus neoformans antiphagocytic protein 1, App1

V Williams, M Del Poeta - Eukaryotic cell, 2011 - Am Soc Microbiol
The cryptococcus-specific protein antiphagocytic protein 1 (App1) regulates Cryptococcus
neoformans virulence by controlling macrophage-driven fungal phagocytosis. This is …