Objective: Image-based localization of medullary thyroid cancer (MTC) and parathyroid
glands would improve the surgical outcomes of these diseases. MTC and parathyroid …

Background Calcium-sensing receptor (CaSR) is expressed by parathyroid cells and thyroid
C-cells (from which medullary thyroid carcinoma [MTC] is derived). A molecular imaging …

Introduction Current imaging techniques have several limitations in detecting parathyroid
glands. We have investigated the calcium-sensing receptor (CaSR) as a potential target for …

AIM: To review the role of the calcium sensing receptor (CASR) in colorectal, breast and
parathyroid cancers and related cell lines, and to discuss the effects of CASR in the setting …

The calcium sensing receptor (CaSR) is a class C G-protein-coupled receptor that is crucial
for the feedback regulation of extracellular free ionised calcium homeostasis. While …

The calcium-sensing receptor (CaSR) is the principal regulator of the secretion of
parathyroid hormone and plays key roles in extracellular calcium (Ca 2+ o) homeostasis. It is …

The calcium-sensing receptor (CaSR)-specific allosteric modulator cinacalcet has
revolutionized the treatment of secondary hyperparathyroidism in patients with chronic …

Bone metastasis is an important prognostic factor in renal cell carcinoma (RCC). The
calcium-sensing receptor (CaSR) has been associated with bone metastasis in several …

The calcium-sensing receptor (CaSR) plays a pivotal role in systemic calcium metabolism by
regulating parathyroid hormone secretion and urinary calcium excretion. The CaSR is …

The calcium sensing receptor (CaSR) is a member of the largest family of cell surface
receptors, the G proteincoupled receptors involved in calcium homeostasis. Studies …