An improved 62Zn/62Cu generator based on a cation exchanger and its fully remote-controlled preparation for clinical use
T Fukumura, K Okada, H Suzuki, R Nakao… - Nuclear medicine and …, 2006 - Elsevier
OBJECTIVE: The goal of this study was to develop an improved 62Zn/62Cu generator based
on cation exchange resin and remote preparation at high radioactivity scale for clinical use …
on cation exchange resin and remote preparation at high radioactivity scale for clinical use …
Chelating ion-exchange methods for the preparation of no-carrier-added 64Cu
S Watanabe, S Watanabe, J Liang, H Hanaoka… - Nuclear medicine and …, 2009 - Elsevier
INTRODUCTION: We have developed a method for producing no-carrier-added 64Cu by
using chelating resin bearing iminodiacetic acid groups. METHODS: We optimized the …
using chelating resin bearing iminodiacetic acid groups. METHODS: We optimized the …
Small-scale production of 67Cu for a preclinical study via the 64Ni (α, p) 67Cu channel
T Ohya, K Nagatsu, H Suzuki, M Fukada… - Nuclear Medicine and …, 2018 - Elsevier
Introduction Copper-67 is an attractive beta emitter for targeted radionuclide therapy.
However, the availability of 67 Cu limits its potential use in a wide range of applications. In …
However, the availability of 67 Cu limits its potential use in a wide range of applications. In …
Efficient preparation of high-quality 64Cu for routine use
T Ohya, K Nagatsu, H Suzuki, M Fukada… - Nuclear Medicine and …, 2016 - Elsevier
Introduction Copper-64 is an attractive radionuclide for positron emission tomography and is
emerging as a radiotherapeutic agent. The demand of 64 Cu with low metallic impurities has …
emerging as a radiotherapeutic agent. The demand of 64 Cu with low metallic impurities has …
High purity production and potential applications of copper-60 and copper-61
DW McCarthy, LA Bass, PD Cutler, RE Shefer… - Nuclear medicine and …, 1999 - Elsevier
Previously we described the high yield production of 64Cu using a target system designed
specifically for low energy, biomedical cyclotrons. In this study, the use of this target system …
specifically for low energy, biomedical cyclotrons. In this study, the use of this target system …
[HTML][HTML] Cyclotron-Based Production of 67Cu for Radionuclide Theranostics via the 70Zn(p,α)67Cu Reaction
SA Brühlmann, M Walther, M Kreller, F Reissig… - Pharmaceuticals, 2023 - mdpi.com
Theranostic matched pairs of radionuclides have aroused interest during the last couple of
years, and in that sense, copper is one element that has a lot to offer, and although 61Cu …
years, and in that sense, copper is one element that has a lot to offer, and although 61Cu …
[HTML][HTML] Large scale production of 64Cu and 67Cu via the 64Zn(n, p)64Cu and 68Zn(n, np/d)67Cu reactions using accelerator neutrons
M Kawabata, S Motoishi, A Ohta, A Motomura… - … of Radioanalytical and …, 2021 - Springer
Abstract Both 64 Cu and 67 Cu are promising radionuclides in nuclear medicine. Production
yields of these radionuclides were quantified by irradiating 55.4 g of natural zinc with …
yields of these radionuclides were quantified by irradiating 55.4 g of natural zinc with …
Production of therapeutic quantities of 64Cu using a 12 MeV cyclotron
A Obata, S Kasamatsu, DW McCarthy, MJ Welch… - Nuclear medicine and …, 2003 - Elsevier
64Cu is a useful radiotracer for positron emission tomography (PET) and a promising
radiotherapy agent for the treatment of cancer. Recently, 64Cu-labeled …
radiotherapy agent for the treatment of cancer. Recently, 64Cu-labeled …
A simple and robust method for radiochemical separation of no-carrier-added 64Cu produced in a research reactor for radiopharmaceutical preparation
R Chakravarty, A Rajeswari, P Shetty… - Applied Radiation and …, 2020 - Elsevier
Copper-64 is an excellent theranostic radiometal that is gaining renewed attention of the
clinical community in the recent times. In order to meet the increasing demand of this …
clinical community in the recent times. In order to meet the increasing demand of this …
Production, separation and supply prospects of 67Cu with the development of fast neutron sources and photonuclear technology
A Gopalakrishna, SV Suryanarayana, H Naik… - Radiochimica …, 2018 - degruyter.com
Experimental investigations have been carried out on the production of a promising
therapeutic radionuclide 67Cu via the 67Zn (n, p) 67Cu, 68Zn (n, x) 67Cu, and 68Zn (γ, p) …
therapeutic radionuclide 67Cu via the 67Zn (n, p) 67Cu, 68Zn (n, x) 67Cu, and 68Zn (γ, p) …