Background Concomitant painful physical symptoms in depressive patients frequently impair
functioning and failure to treat these symptoms may adversely impact treatment outcomes of …

Painful physical symptoms (PPS) are common in patients with depression. Our objective
was to evaluate the presence of PPS in a sample of SSRI non-or partial-responders with …

Background: This study was designed to assess clinical and functional outcomes associated
with switching to duloxetine treatment in patients with major depressive disorder (MDD) …

Objective This post hoc analysis of a multicenter, single‐arm, open‐label trial (the Attributes
of Response in Depressed Patients Switched to Treatment with Duloxetine [ARDENT] study) …

Background. Patients with major depressive disorder (MDD) frequently report one or more
pain symptoms. To explore the relationship between improvement in pain symptoms and …

Background Approximately two-thirds of patients with depression experience physical pain
symptoms. Coexisting pain complicates the treatment of depression and is associated with …

Objective: To compare 2 methods of switching selective serotonin reuptake inhibitor (SSRI)
nonresponders or partial responders to duloxetine. Method: Adult outpatients with DSM-IV …

Objective We determined if early improvement in painful physical symptoms (PPS) can be a
predictor of remission in the treatment of major depressive disorder (MDD). Methods We …

Objective Antidepressant switch is a commonly used strategy in the absence of an adequate
response, but optimum timing is not well established. We compared the efficacy of an early …

Objective: Painful physical symptoms are common in patients with major depressive
disorder (MDD) and can negatively affect patient outcomes. Duloxetine has demonstrated …