Mechanisms and clinical importance of bacteriophage resistance
JE Egido, AR Costa… - FEMS microbiology …, 2022 - academic.oup.com
We are in the midst of a golden age of uncovering defense systems against bacteriophages.
Apart from the fundamental interest in these defense systems, and revolutionary applications …
Apart from the fundamental interest in these defense systems, and revolutionary applications …
The arms race between bacteria and their phage foes
HG Hampton, BNJ Watson, PC Fineran - Nature, 2020 - nature.com
Bacteria are under immense evolutionary pressure from their viral invaders—
bacteriophages. Bacteria have evolved numerous immune mechanisms, both innate and …
bacteriophages. Bacteria have evolved numerous immune mechanisms, both innate and …
Revenge of the phages: defeating bacterial defences
JE Samson, AH Magadán, M Sabri… - Nature Reviews …, 2013 - nature.com
Bacteria and their viral predators (bacteriophages) are locked in a constant battle. In order to
proliferate in phage-rich environments, bacteria have an impressive arsenal of defence …
proliferate in phage-rich environments, bacteria have an impressive arsenal of defence …
Remarkable mechanisms in microbes to resist phage infections
RL Dy, C Richter, GPC Salmond… - Annual review of …, 2014 - annualreviews.org
Bacteriophages (phages) specifically infect bacteria and are the most abundant biological
entities on Earth. The constant exposure to phage infection imposes a strong selective …
entities on Earth. The constant exposure to phage infection imposes a strong selective …
Conquering CRISPR: how phages overcome bacterial adaptive immunity
The rise of antibiotic-resistant bacteria has led to renewed interest in the use of their natural
enemies, phages, for the prevention and treatment of infections. However, phage therapy …
enemies, phages, for the prevention and treatment of infections. However, phage therapy …
[HTML][HTML] Battling phages: how bacteria defend against viral attack
KD Seed - PLoS pathogens, 2015 - journals.plos.org
Bacteriophages (phages) are accomplished, bacteria-specific, viral predators with far-
reaching impact: from the food and biotechnology industries [1] to global nutrient cycling [2] …
reaching impact: from the food and biotechnology industries [1] to global nutrient cycling [2] …
Fitness trade-offs resulting from bacteriophage resistance potentiate synergistic antibacterial strategies
MR Mangalea, BA Duerkop - Infection and immunity, 2020 - Am Soc Microbiol
Bacteria that cause life-threatening infections in humans are becoming increasingly difficult
to treat. In some instances, this is due to intrinsic and acquired antibiotic resistance …
to treat. In some instances, this is due to intrinsic and acquired antibiotic resistance …
A century of the phage: past, present and future
GPC Salmond, PC Fineran - Nature Reviews Microbiology, 2015 - nature.com
Viruses that infect bacteria (bacteriophages; also known as phages) were discovered 100
years ago. Since then, phage research has transformed fundamental and translational …
years ago. Since then, phage research has transformed fundamental and translational …
[PDF][PDF] Contemporary phage biology: from classic models to new insights
Bacteriophages, discovered about a century ago, have been pivotal as models for
understanding the fundamental principles of molecular biology. While interest in phage …
understanding the fundamental principles of molecular biology. While interest in phage …
[HTML][HTML] Resistance development to bacteriophages occurring during bacteriophage therapy
F Oechslin - Viruses, 2018 - mdpi.com
Bacteriophage (phage) therapy, ie, the use of viruses that infect bacteria as antimicrobial
agents, is a promising alternative to conventional antibiotics. Indeed, resistance to antibiotics …
agents, is a promising alternative to conventional antibiotics. Indeed, resistance to antibiotics …