Citrus fruit has long been considered a healthy food, but its role and detailed mechanism in
lifespan extension are not clear. Here, by using the nematode C. elegans, we identified that …

Aging is a major international concern that brings formidable socioeconomic and healthcare
challenges. Small molecules capable of improving the health of older individuals are being …

Extracts of the Chinese plant Polygonum multiflorum (PME) are used for medicinal purposes
as well as food supplement due to anti-aging effects. Despite of the common use of these …

Myricetin is a naturally occurring flavonol found in many plant based food sources. It
increases the lifespan of Caenorhabditis elegans, but the molecular mechanisms are not yet …

In the long history of traditional Chinese medicine, single herbs and complex formulas have
been suggested to increase lifespan. However, the identification of single molecules …

Delay aging, especially in healthy life extension, brought the most interest to the medical
field. Searching for anti-aging drugs with relative safety profiles bring natural products in …

Compounds that delay aging might also postpone age-related diseases and extend
healthspan in humans. Icariin is a flavonol extracted from several plant species of the …

Background One of the most important challenges in the study of aging is to discover
compounds with longevity-promoting activities and to unravel their underlying mechanisms …

Drugs or compounds have been shown to promote longevity in various approaches. We
used Drosophila to explore novel natural compounds can be applied to anti-aging. Here we …

Aging is the major risk factor for many human diseases and degeneration. Thus, clinically
effective medicine could delay the process of aging and aging-related diseases are …