Aspergillus fumigatus-induced early inflammatory response in pulmonary microvascular endothelial cells: Role of p38 MAPK and inhibition by silibinin
J Song, W Pan, Y Sun, J Han, W Shi, W Liao - International …, 2017 - Elsevier
Human invasive pulmonary aspergillosis (IPA) is a serious infectious disease mainly caused
by Aspergillus fumigatus (A. fumigatus). Pulmonary microvascular endothelial cells …
by Aspergillus fumigatus (A. fumigatus). Pulmonary microvascular endothelial cells …
Aspergillus fumigatus Stimulates Leukocyte Adhesion Molecules and Cytokine Production by Endothelial Cells In Vitro and during Invasive Pulmonary Disease
LY Chiang, DC Sheppard, FN Gravelat… - Infection and …, 2008 - Am Soc Microbiol
Invasive aspergillosis is characterized by hyphal invasion of the blood vessels, which
contributes to the pathogenesis of this disease. During this angioinvasion, Aspergillus …
contributes to the pathogenesis of this disease. During this angioinvasion, Aspergillus …
Interleukin‐12 and interleukin‐2 alone or in combination against the infection in invasive pulmonary aspergillosis mouse model
CR Zhang, JC Lin, WM Xu, M Li, HS Ye, WL Cui… - Mycoses, 2013 - Wiley Online Library
Aspergillus fumigatus is an intracellular opportunistic fungus causing invasive pulmonary
mycosis, characterised by hyphal invasion and destruction of pulmonary tissue. Th1 …
mycosis, characterised by hyphal invasion and destruction of pulmonary tissue. Th1 …
Use of a human small airway epithelial cell line to study the interactions of Aspergillus fumigatus with pulmonary epithelial cells
During the initiation of invasive aspergillosis, inhaled Aspergillus fumigatus conidia are
deposited on the epithelial cells lining the bronchi, terminal bronchioles, and alveoli. While …
deposited on the epithelial cells lining the bronchi, terminal bronchioles, and alveoli. While …
Aspergillus fumigatus Induces the Release of IL-8 and MCP-1 by Activating Nuclear Transcription Through Dectin-1 and CR3 Receptors in Alveolar Epithelial Cells
Y Liu, Z Li, S Wang, C Zhang, L Han, Q Sun, X Han - Current Microbiology, 2021 - Springer
Invasive pulmonary aspergillosis induced by the pathogenic fungus Aspergillus fumigatus is
one of the common fatal complications in immunocompromised patients. Lung epithelial …
one of the common fatal complications in immunocompromised patients. Lung epithelial …
Virulence capacity of different Aspergillus species from invasive pulmonary aspergillosis
B Chen, G Qian, Z Yang, N Zhang, Y Jiang… - Frontiers in …, 2023 - frontiersin.org
Introduction The opportunistic filamentous fungus Aspergillus causes invasive pulmonary
aspergillosis (IPA) that often turns into a fatal infection in immunocompromised hosts …
aspergillosis (IPA) that often turns into a fatal infection in immunocompromised hosts …
Aspergillus fumigatus germ tube growth and not conidia ingestion induces expression of inflammatory mediator genes in the human lung epithelial cell line A549
AP Bellanger, L Millon, K Khoufache… - Journal of Medical …, 2009 - microbiologyresearch.org
Inhalation of conidia is the main cause of invasive pulmonary aspergillosis (IPA) and the
respiratory epithelium is the first line of defence. To explore the triggering factor for the …
respiratory epithelium is the first line of defence. To explore the triggering factor for the …
Interaction of Aspergillus fumigatus with the alveolar macrophage
M Dubourdeau, R Athman, V Balloy, B Philippe… - Medical …, 2006 - Taylor & Francis
Aspergillus fumigatus is a human pathogen, able to cause invasive aspergillosis in
immunosuppressed patients. In the immunocompetent situation inhaled conidia are easily …
immunosuppressed patients. In the immunocompetent situation inhaled conidia are easily …
Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 …
V Balloy, JM Sallenave, Y Wu, L Touqui… - Journal of biological …, 2008 - ASBMB
Previous studies have established that phagocytes are key cells of the pulmonary innate
immune defense against A. fumigatus, an opportunistic fungus responsible of invasive …
immune defense against A. fumigatus, an opportunistic fungus responsible of invasive …
IL-1α and IL-1β play non-redundant roles in limiting in vivo Aspergillus fumigatus pulmonary growth (P3092)
J Obar, M Lehmann, A Caffrey, C Watschke… - The Journal of …, 2013 - journals.aai.org
Aspergillus fumigatus is a mold that causes severe pulmonary infections in humans, such as
invasive pulmonary Aspergillosis (IPA). Currently, our knowledge of how A. fumigatus …
invasive pulmonary Aspergillosis (IPA). Currently, our knowledge of how A. fumigatus …