Objective This study aimed to evaluate glycolysis inhibitor which can effectively ameliorate
arthritis by inhibiting synoviocyte activation through AMPK/NF-кB pathway in AA rats …

Objective To investigate the role of glycogen metabolism in regulating rheumatoid fibroblast-
like synoviocyte (FLS)-mediated synovial inflammation and its underlying mechanism …

Objective This study investigated the effectiveness of arecoline hydrobromide (AH) on the
functions of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs) and collagen …

Recent studies indicate that glucose metabolism is altered in rheumatoid arthritis. We
hypothesize that Pkm2, as a key regulatory enzyme of glycolysis pathway, triggers the …

Geniposide (GE), an iridoid glycoside compound derived from Gardenia jasminoides Ellis
fruit, is known to have anti-inflammatory and immunoregulatory activities. The aim of this …

Osteoarthritis (OA) causes severe and functional dysfunction due to abnormal inflammation.
The objective of this study was to evaluate the effect of Harpagide (HPG) on TNF-α-induced …

Context Ginsenoside metabolite compound K (CK) is an active metabolite produced by
ginsenosides in vivo that has an anti-arthritic effect related to the glucocorticoid receptor …

Objective: Recently, we found that administration of glucosamine to adjuvant arthritis, a
model for rheumatoid arthritis, suppressed the progression of arthritis in rats. To clarify its …

Macrophages are highly plastic cells critical for the development of rheumatoid arthritis (RA).
Macrophages exhibit a high degree of pro-inflammatory plasticity in RA, accompanied by a …

Background The current study was intended to investigate the effect of ketamine (KET) on
complete Freund's adjuvant (CFA)-induced arthritis in rats. Methods The CFA was …