[HTML][HTML] New drugs for the treatment of hyperkalemia in patients treated with renin-angiotensin-aldosterone system inhibitors—hype or hope?

J Tamargo, R Caballero, E Delpon - Discovery Medicine, 2014 - discoverymedicine.com
Hyperkalemia (serum potassium> 5.5 mmol/L) may result from increased potassium intake,
impaired distribution between the intracellular and extracellular spaces, and/or reduced …

New therapeutic approaches for the treatment of hyperkalemia in patients treated with renin-angiotensin-aldosterone system inhibitors

J Tamargo, R Caballero, E Delpon - Cardiovascular Drugs and Therapy, 2018 - Springer
Abstract Hyperkalemia (serum potassium> 5.5 mEq/L) is a common clinical problem in
patients with chronic kidney disease, hypertension, diabetes, and heart failure. It can result …

Patiromer: the first potassium binder approved in over 50 years

BN Vu, AM De Castro, D Shottland… - Cardiology in …, 2016 - journals.lww.com
For over 50 years, there have been limited options for the management of hyperkalemia,
especially among patients with chronic kidney disease (CKD), diabetic nephropathy …

Clinical utility of patiromer, sodium zirconium cyclosilicate, and sodium polystyrene sulfonate for the treatment of hyperkalemia: an evidence-based review

MV Beccar, CJ Meaney - Core evidence, 2017 - Taylor & Francis
Introduction: Hyperkalemia is a serious medical condition that often manifests in patients
with chronic kidney disease and heart failure. Renin–angiotensin–aldosterone system …

[HTML][HTML] Effectiveness of patiromer in the treatment of hyperkalemia in chronic kidney disease patients with hypertension on diuretics

MR Weir, MR Mayo, D Garza, SA Arthur… - Journal of …, 2017 - journals.lww.com
Objective: Recurrent hyperkalemia frequently limits use of renin–angiotensin–aldosterone
system inhibitors (RAASi) in chronic kidney disease (CKD) patients with hypertension …

Complications and management of hyperkalemia: implications for the use of the novel cation exchangers zirconium cyclosilicate and patiromer.

L Noureddine, BS Dixon - 2015 - cabidigitallibrary.org
Hyperkalemia is a serious and common clinical condition associated with increased
morbidity and death. The risk of hyperkalemia is increased in patients with chronic kidney …

Effect of patiromer on serum potassium level in patients with hyperkalemia and diabetic kidney disease: the AMETHYST-DN randomized clinical trial

GL Bakris, B Pitt, MR Weir, MW Freeman, MR Mayo… - Jama, 2015 - jamanetwork.com
Importance Hyperkalemia is a potentially life-threatening condition predominantly seen in
patients treated with renin-angiotensin-aldosterone system (RAAS) inhibitors with stage 3 or …

Managing hyperkalemia: stepping into a new frontier

AQ Pham, J Sexton, D Wimer, I Rana… - Journal of Pharmacy …, 2017 - journals.sagepub.com
Maintaining potassium balance in the body is essential for cellular function. Even a slight
increase in normal serum potassium levels (3.5-5.0 mEq/L) can interfere with metabolism …

Mechanism of action and pharmacology of patiromer, a nonabsorbed cross-linked polymer that lowers serum potassium concentration in patients with hyperkalemia

L Li, SD Harrison, MJ Cope, C Park… - Journal of …, 2016 - journals.sagepub.com
Hyperkalemia is a potentially life-threatening condition, and patients who have chronic
kidney disease, who are diabetic, or who are taking renin–angiotensin–aldosterone system …

Advances in treatment of hyperkalemia in chronic kidney disease

PA Sarafidis, PI Georgianos… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Hyperkalemia is a frequent electrolyte disorder associated with life-threatening
cardiac arrhythmias and sudden death. Patients prone to hyperkalemia have chronic kidney …