In the present study, we investigated whether dynamic and static allodynia would be
developed in the affected dermatome in murine models of herpetic pain and postherpetic …

In the present study, we investigated whether the peripherally acting µ-opioid receptor
agonist loperamide would inhibit allodynia in the non-inflamed dermatome of mice with …

Percutaneous inoculation with herpes simplex virus type-1 brings about herpes zoster-like
skin lesions, tactile allodynia, and mechanical hyperalgesia in mice. This study was …

We have recently found that the infection with herpes simplex virus type-1 (HSV-1) of
primary sensory neurons induces nociceptive hypersensitivity to noxious mechanical …

Mechanical dynamic allodynia is a hallmark symptom of postherpetic neuralgia, but the
mechanisms are unclear. This study examined the participation of injury to sensory C-fiber …

This review describes my research for the past 39 years regarding the pharmacology of pain
and analgesia. We have demonstrated that the descending noradrenergic system is …

The effects of systemic and local injections of gabapentin, a novel anticonvulsant agent,
were tested on nociceptive behaviors in mice with acute herpetic pain. Transdermal infection …

The aim of the present study was to investigate the role of primary afferent fibres with
polymodal nociceptors in the various pain symptoms and signs associated with post …

Background Postherpetic neuralgia is pain that persists long after the disappearance of the
cutaneous lesions of herpes zoster. However, the mechanisms of this delayed pain are …

The inoculation of mice with herpes simplex virus type-1 (HSV-1) causes herpes zoster-like
skin lesions and pain-related responses (tactile allodynia and mechanical hyperalgesia) …