BACKGROUND: Hormone replacement therapy increases the number and quality of grafts
recovered from brain-dead organ donors. Arginine vasopressin (AVP) has also been shown …

Background Hormone replacement therapy (HRT) is becoming more common when
managing brain-dead donors. Arginine vasopressin (AVP) is associated with benefits but is …

In a prospective study, we documented the hemodynamic effects of conventional donor
maintenance in 24 brain-dead organ donors. Patients were then randomized to receive …

Background. Brain death results in adverse pathophysiologic effects in many cadaveric
donors, resulting in cardiovascular instability and poor organ perfusion. Hormonal …

Background Refinements in donor management have resulted in increased numbers and
quality of grafts after neurologic death. We hypothesize that the increased use of hormone …

Significant systemic changes occur following neurologic insult and subsequent brain death.
If left untreated, the hemodynamic instability and neuroendocrine alterations that ensue may …

The management of brain-dead organ donors is complex. The use of inotropic agents and
replacement of depleted hormones (hormonal replacement therapy) is crucial for successful …

There are still many controversial aspects regarding which method is best for managing
organ donors to prevent, lessen, or even reverse the organ alterations associated with brain …

Organ transplantation often depends on obtaining functioning organs from a donor who has
recently died. This review presents a structured approach to management of the care of the …

Background. Brain death results in cardiovascular instability and poor organ perfusion in
many brain-dead donors. Hormonal resuscitation stabilizes certain brain-dead donors and is …