Aims/hypothesis Impaired regulation of lipolysis and accumulation of lipid intermediates may
contribute to obesity-related insulin resistance and type 2 diabetes mellitus. We investigated …

The aim of this study was to evaluate in premenopausal women (six endurance-trained
nonobese, six sedentary nonobese, and five sedentary obese) the suppression of whole …

Upper‐body/visceral obesity is associated with abnormalities of free fatty acid (FFA)
metabolism and greater risk of developing type 2 diabetes compared with lower‐body …

Insulin resistance is frequently associated with increased lipid content in muscle and liver.
Insulin excess stimulates tissue lipid accumulation. To examine the effects of insulin and …

Obesity-induced insulin resistance is a major risk factor for the development of type 2
diabetes. Basal fat cell lipolysis (ie, fat cell triacylglycerol breakdown into fatty acids and …

Aims/hypothesis. Both patients with Type II (non-insulin-dependent) diabetes mellitus and
normoglycaemic, insulin resistant subjects were shown to have an increased lipid content in …

The increased risk of hypoglycemia during intensified treatment of type 1 diabetes mellitus
(T1DM) patients, who have a deficient glucagon secretory response, is largely attributed to …

The metabolic and isotopic profiles of glycerol in skeletal muscle were examined using
awake, fasted lean and high-fat-induced obese rats, and hyperinsulinemic-euglycemic …

Aims/hypothesis The aims of this study were to determine the role of lipolysis in
hypoglycaemia and define the underlying intracellular mechanisms. Methods Nine healthy …

In addition to sc and visceral fat deposits, muscle has been shown to contain relevant
amounts of lipids whose breakdown is subject to hormonal regulation. The aim of the …