The distributed genome hypothesis (DGH) states that each strain within a bacterial species
receives a unique distribution of genes from a population-based supragenome that is many …

Pseudomonas aeruginosa, a ubiquitous gram-negative bacterium, is capable of colonizing a
wide range of environmental niches and can also cause serious infections in humans. In …

Pseudomonas aeruginosa PAO1 is the most commonly used strain for research on this
ubiquitous and metabolically versatile opportunistic pathogen. Strain PAO1, a derivative of …

Most known virulence determinants of Pseudomonas aeruginosa are remarkably conserved
in this bacterium's core genome, yet individual strains differ significantly in virulence. One …

Recent work has signaled the beginning of the comparative genomics era for analysis of the
important pathogen Pseudomonas aeruginosa. Comprehensive systematization of …

Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Whole-genome shotgun sequencing was used to study the sequence variation of three
Pseudomonas aeruginosa isolates, two from clonal infections of cystic fibrosis patients and …

Pseudomonas aeruginosa is an opportunistic bacterial pathogen able to thrive in highly
diverse ecological niches and to infect compromised patients. Its genome exhibits a mosaic …

Pseudomonas aeruginosa is an opportunistic pathogen found ubiquitously in the
environment and commonly associated with airway infection in patients with cystic fibrosis …

Background The constant increase in development and spread of bacterial resistance to
antibiotics poses a serious threat to human health. New sequencing technologies are now …