Background The COVID-19 pandemic has highlighted the world-changing impact of
infectious diseases to all 7.8 billion people. Our distant ancestors were aware of the …

Background Fever without localizing features, hereafter referred to as fever or febrile illness,
is among the most common reasons for persons in low-resource areas to seek health care …

Introduction Febrile illnesses (FI) represent a typical spectrum of diseases in low-resource
settings, either in isolation or with other common symptoms. They contribute substantially to …

Background An increasing use of point of care diagnostic tests that exclude malaria, coupled
with a declining malaria burden in many endemic countries, is highlighting the lack of ability …

Introduction: With the ability to diagnose malaria with rapid diagnostic tests (mRDT), interest
in improving diagnostics for non-malarial fevers has increased. Understanding how health …

Background Malaria incidence is in decline in many parts of SE Asia leading to a decreasing
proportion of febrile illness that is attributable to malaria. However in the absence of rapid …

In rural areas of South and Southeast Asia malaria is declining but febrile illnesses still
account for substantial morbidity and mortality. Village health workers (VHWs) are often the …

Malaria and other febrile illnesses are very common especially in children in developing
countries. Due to reliance on clinical algorithms for diagnosis in resource-poor settings, most …

Background In malaria-endemic countries, febrile episodes caused by diseases other than
malaria are a growing concern. However, limited knowledge of the prevalent etiologic …

Fever is a leading reason for people to seek healthcare in the tropics. 1 Given the non-
specific clinical presentation of many infections causing fever and the limited clinical …