[HTML][HTML] Evolution and spread of Plasmodium falciparum mutations associated with resistance to sulfadoxine–pyrimethamine in central Africa: a cross-sectional study

E Guémas, R Coppée, S Ménard, M Du Manoir… - The Lancet …, 2023 - thelancet.com
Background Efficacy of sulfadoxine–pyrimethamine, the malaria chemoprophylaxis used in
pregnant women, and in children when combined with amodiaquine, is threatened by the …

Molecular determinants of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates from Central Africa between 2016 and 2021: wide geographic …

X Wang, X Zhang, H Chen, Q Lu, W Ruan… - Microbiology …, 2022 - Am Soc Microbiol
Sulfadoxine-pyrimethamine (SP) resistance impairs the efficacy of antimalarial drugs.
Monitoring molecular markers in exported malaria infections provides an efficient way to …

High prevalence of PfdhfrPfdhps quadruple mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates from Bioko Island …

T Jiang, J Chen, H Fu, K Wu, Y Yao, JUM Eyi… - Malaria journal, 2019 - Springer
Background Sulfadoxine–pyrimethamine (SP) is recommended for intermittent preventive
treatment of malaria in Africa. However, increasing SP resistance (SPR) affects the …

Increased prevalence of pfdhfr and pfdhps mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates from Jazan Region …

AM Madkhali, HM Al-Mekhlafi, WM Atroosh… - Malaria journal, 2020 - Springer
Background Despite significant progress in eliminating malaria from the Kingdom of Saudi
Arabia, the disease is still endemic in the southwestern region of the country. Artesunate …

Temporal evolution of sulfadoxine-pyrimethamine resistance genotypes and genetic diversity in response to a decade of increased interventions against Plasmodium …

LN Amenga-Etego, V Asoala, G Agongo, C Jacob… - Malaria Journal, 2021 - Springer
Background Anti-malarial drug resistance remains a key concern for the global fight against
malaria. In Ghana sulfadoxine-pyrimethamine (SP) is used for intermittent preventive …

Different origin and dispersal of sulfadoxine-resistant Plasmodium falciparum haplotypes between Eastern Africa and Democratic Republic of Congo

V Baraka, C Delgado-Ratto, S Nag… - International journal of …, 2017 - Elsevier
Sulfadoxine/pyrimethamine (SP) is still used for malaria control in sub-Saharan Africa;
however, widespread resistance is a major concern. This study aimed to determine the …

Trends in Molecular Markers Associated with Resistance to Sulfadoxine-Pyrimethamine (SP) Among Plasmodium falciparum Isolates on Bioko Island, Equatorial …

LY Lin, J Li, HY Huang, XY Liang, TT Jiang… - Infection and Drug …, 2020 - Taylor & Francis
Purpose Antimalarial drug resistance is one of the major challenges in global efforts to
control and eliminate malaria. In 2006, sulfadoxine-pyrimethamine (SP) replaced with …

Analysis of sulphadoxine/pyrimethamine resistance-conferring mutations of Plasmodium falciparum from Mozambique reveals the absence of the dihydrofolate …

N Fernandes, P Figueiredo, VE Do Rosário, P Cravo - Malaria Journal, 2007 - Springer
Background Plasmodium falciparum is the predominant human malaria species in
Mozambique and a lead cause of mortality among children and pregnant women …

Prevalence of sulfadoxine–pyrimethamine resistance-associated mutations in dhfr and dhps genes of Plasmodium falciparum three years after SP withdrawal in Bahir …

E Hailemeskel, M Kassa, G Taddesse, H Mohammed… - Acta tropica, 2013 - Elsevier
Ethiopia changed the first-line anti-malarial drug for uncomplicated Plasmodium falciparum
malaria from sulfadoxine–pyrimethamine (SP) to Coartem® in 2004 following nation-wide …

PA-382 Trends in sulfadoxine-pyrimethamine resistance molecular markers among plasmodium falciparum isolates before and after adopting seasonal malaria …

F Bohissou, P Sondo, J Inoue, T Rouamba… - 2023 - gh.bmj.com
Background Despite various efforts to control malaria among children, the disease remains
a leading cause of morbidity and mortality worldwide. In the Sahel region, including Burkina …