Chlamydial 60-kDa heat shock proteins (cHsp60s) are known to play a prominent role in the
immunopathogenesis of disease. It is also known that several stress-inducing growth …

The mucosal pathogen Chlamydia trachomatis affects hundreds of millions of people
worldwide and is a significant cause of sexually transmitted disease. Although most acute …

Chlamydia trachomatis is an obligate intracellular bacterium that infects chiefly urogenital
and ocular epithelial cells. In some infected women the microorganism migrates to the upper …

Ocular and urogenital tract infections with Chlamydia trachomatis can progress to chronic
inflammatory diseases that produce blindness and tubal infertility. The pathophysiology of …

Chlamydia trachomatis is a major cause of ocular and genital tract infections of humans.
These infections generally resolve without adverse sequelae, but occasionally severe …

Heat shock proteins (HSPs) of most pathogens, including Chlamydia, are major immune
targets of both humoral‐and cell‐mediated immune mechanisms. During the last decade …

A primate model of chlamydial pelvic inflammatory disease was used to characterize serum
antibody responses to the 60 kDa chlamydial heat shock protein (CHSP60). Forty monkeys …

Background The magnitude of reproductive morbidity associated with sexually transmitted
Chlamydia trachomatis infection is enormous. Association of antibodies to chlamydial heat …

The immunopathologic sequelae of chlamydial infection are correlated with immune
responses to the Chlamydia trachomatis heat shock protein 60 (hsp60). One pathogenic …

We isolated and sequenced the gene for the chlamydial heat shock protein 60 (HSP-60)
from a Chlamydia trachomatis genomic library by molecular genetic methods. The DNA …