[HTML][HTML] Efficacy of zoledronic acid for chronic low back pain associated with Modic changes in magnetic resonance imaging
K Koivisto, E Kyllönen, M Haapea, J Niinimäki… - BMC Musculoskeletal …, 2014 - Springer
Background Modic changes (MC) are associated with low back pain (LBP), but effective
treatments are lacking. The aim of this randomized, placebo-controlled, double-blinded trial …
treatments are lacking. The aim of this randomized, placebo-controlled, double-blinded trial …
[HTML][HTML] The effect of zoledronic acid on type and volume of Modic changes among patients with low back pain
K Koivisto, J Järvinen, J Karppinen, M Haapea… - BMC Musculoskeletal …, 2017 - Springer
Background Modic changes (MC) are associated with low back pain (LBP). In this study, we
compared changes in size and type of MC, after a single intravenous infusion of 5 mg …
compared changes in size and type of MC, after a single intravenous infusion of 5 mg …
Effect of zoledronic acid and denosumab in patients with low back pain and modic change: a proof‐of‐principle trial
The aim of this study was to evaluate the effect of zoledronic acid (ZA) and denosumab on
low back pain (LBP) and Modic change (MC) over 6 months. Adults aged≥ 40 years with …
low back pain (LBP) and Modic change (MC) over 6 months. Adults aged≥ 40 years with …
[HTML][HTML] The effect of zoledronic acid on serum biomarkers among patients with chronic low back pain and modic changes in lumbar magnetic resonance imaging
K Koivisto, J Karppinen, M Haapea, J Järvinen… - Diagnostics, 2019 - mdpi.com
The aim of the current study was to compare changes in serum biomarkers, including
inflammatory mediators, signaling molecules, growth factors and markers of bone turnover …
inflammatory mediators, signaling molecules, growth factors and markers of bone turnover …
[HTML][HTML] Is the presence of modic changes associated with the outcomes of different treatments? A systematic critical review
RK Jensen, C Leboeuf-Yde - BMC musculoskeletal disorders, 2011 - Springer
Abstract Background Modic changes (MCs) have been identified as a diagnostic subgroup
associated with low back pain (LBP). The aetiology of MCs is still unknown and there is no …
associated with low back pain (LBP). The aetiology of MCs is still unknown and there is no …
Type 1 Modic changes was a significant risk factor for 1-year outcome in sick-listed low back pain patients: a nested cohort study using magnetic resonance imaging of …
OK Jensen, CV Nielsen, JS Sørensen… - The Spine Journal, 2014 - Elsevier
Background context It is not clear whether Modic changes (MC) is associated with low back
pain (LBP) outcome. Purpose To study associations between baseline degenerative …
pain (LBP) outcome. Purpose To study associations between baseline degenerative …
Clinical efficacy of calcitonin compared to diclofenac sodium in chronic nonspecific low back pain with type I Modic changes: a retrospective study
J Zhou, T Li, L Li, Y Xue - Journal of Pain Research, 2018 - Taylor & Francis
Background The objective of this study was to compare the efficacy of calcitonin with
diclofenac sodium in the treatment of patients with nonspecific low back pain (LBP) and type …
diclofenac sodium in the treatment of patients with nonspecific low back pain (LBP) and type …
Modic changes are not associated with long-term pain and disability: a cohort study with 13-year follow-up
PM Udby, T Bendix, S Ohrt-Nissen, MR Lassen… - Spine, 2019 - journals.lww.com
Study Design. A comparative cohort study with 13-year follow-up. Objective. To assess
whether Modic changes (MCs) are associated with long-term physical disability, back pain …
whether Modic changes (MCs) are associated with long-term physical disability, back pain …
[HTML][HTML] Analyzing the influence of modic changes on patients with lower back pain undergoing conservative treatment
Y Chen, H Yang, L Zhang, Y Wang, J Zou - Pain Research and …, 2019 - hindawi.com
Objective. This study aimed to investigate if the presence of Modic changes (MCs) was
correlated with lower back pain (LBP) and LBP-related disability in patients who underwent …
correlated with lower back pain (LBP) and LBP-related disability in patients who underwent …
[HTML][HTML] Association between changes in lumbar Modic changes and low back symptoms over a two-year period
J Järvinen, J Karppinen, J Niinimäki, M Haapea… - BMC musculoskeletal …, 2015 - Springer
Abstract Background The association of Modic changes (MC) with low back pain (LBP) is
unclear. The purpose of our study was to investigate the associations between the extent of …
unclear. The purpose of our study was to investigate the associations between the extent of …