Mesenchymal stem cells: biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease

AR Williams, JM Hare - Circulation research, 2011 - Am Heart Assoc
Mesenchymal stem cells (MSCs) are a prototypical adult stem cell with capacity for self-
renewal and differentiation with a broad tissue distribution. Initially described in bone …

Mesenchymal stem cell therapy for heart disease

M Gnecchi, E Cervio - Mesenchymal stem cell therapy, 2013 - Springer
Mesenchymal stem cells (MSC) are adult stem cells with capacity for self-renewal and multi-
lineage differentiation. Initially described in bone marrow, MSC are also present in other …

Concise review: mesenchymal stem cells in cardiovascular regeneration: emerging research directions and clinical applications

M Majka, M Sułkowski, B Badyra… - Stem cells translational …, 2017 - academic.oup.com
Experimental and early clinical data suggest that, due to several unique properties,
mesenchymal stem cells (MSCs) may be more effective than other cell types for diseases …

Concise review: rational use of mesenchymal stem cells in the treatment of ischemic heart disease

MR Ward, A Abadeh, KA Connelly - Stem cells translational …, 2018 - academic.oup.com
The capacity of stem and progenitor cells to stimulate cardiac regeneration has been studied
for almost 20 years, with very promising preclinical data and mixed clinical results. Several …

Mesenchymal stem cells in cardiology

IA White, C Sanina, W Balkan, JM Hare - Mesenchymal Stem Cells …, 2016 - Springer
Cardiovascular disease (CVD) accounts for more deaths globally than any other single
disease. There are on average 1.5 million episodes of myocardial infarction (heart attack) …

[HTML][HTML] Mesenchymal stem cell (MSCs) therapy for ischemic heart disease: a promising frontier

MS Poomani, I Mariappan, R Perumal, R Regurajan… - Global Heart, 2022 - ncbi.nlm.nih.gov
Although tremendous progress has been made in conventional treatment for ischemic heart
disease, it still remains a major cause of death and disability. Cell-based therapeutics holds …

Use of mesenchymal stem cells for therapy of cardiac disease

V Karantalis, JM Hare - Circulation research, 2015 - Am Heart Assoc
Despite substantial clinical advances over the past 65 years, cardiovascular disease
remains the leading cause of death in America. The past 15 years has witnessed major …

Rebuilding the damaged heart: mesenchymal stem cells, cell-based therapy, and engineered heart tissue

S Golpanian, A Wolf, KE Hatzistergos… - Physiological …, 2016 - journals.physiology.org
Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

Mesenchymal stem cells and their potential as cardiac therapeutics

MF Pittenger, BJ Martin - Circulation research, 2004 - Am Heart Assoc
Mesenchymal stem cells (MSCs) represent a stem cell population present in adult tissues
that can be isolated, expanded in culture, and characterized in vitro and in vivo. MSCs …

Mesenchymal stem cells for cardiac regenerative therapy

KH Schuleri, AJ Boyle, JM Hare - Bone marrow-derived progenitors, 2007 - Springer
Until recently, the concept of treating the injured or failing heart by generating new functional
myocardium was considered physiologically impossible. Major scientific strides in the past …