The multigene family of rabbit IFN-α (RbIFN-α) is located on chromosome 1, which shows
seven functional genes in type I IFN locus. A novel RbIFN-α that remains unlocated in the …

A bovine IFN-ε (BoIFN-ε) gene was amplified from bovine liver genomic DNA consisting of a
463 bp partial 5′ UTR, 582 bp complete ORF and 171 bp partial 3′ UTR, which encodes a …

A novel bovine interferon-ω (BoIFN-ω) gene, which encodes a protein of 195 amino acids
with a 23-amino acid signal peptide, was amplified from bovine liver genomic DNA through …

IFN-α has been shown to induce both antiviral and antiproliferative activities in animals. This
report describes the biological activity of five recently identified feline IFN-α subtypes …

The antigenic properties of human hybrid IFN-α8 (60)/α1 (92)/α 8 were compared with those
of human IFN alpha 1 and IFN-α 2 using monoclonal antibodies (mAb). Hybrid IFN …

In this study, we provide the first comprehensive annotation of the entire family of canine
interferons (IFNs). Canine IFN-ɛ (IFNE), IFN-κ (IFNK), and IFN-λ (IFNL) were discovered for …

Background Many studies have investigated the characteristics and biological activities of
type III interferon (IFN), finding that it has similar features to type I IFN but also unique actions …

Interferon (IFN) is thought to play an important role in the vertebrate immune system, but
systemic knowledge of IFN evolution has yet to be elucidated. To evaluate the phylogenic …

The type I IFNs play a major role in the first line of defense against virus infections. In this
study, the type I IFN gene designated gsIFN was identified and characterized in the Chinese …

The interferons (IFNs) are a large family of multifunctional secreted protein involved in
antiviral defense, cell growth regulation, and immune activation. The human IFNs are used …