Analytical measurement and clinical relevance of vitamin D3 C3-epimer
D Bailey, K Veljkovic, M Yazdanpanah, K Adeli - Clinical biochemistry, 2013 - Elsevier
With an ever-increasing clinical interest in vitamin D insufficiency, numerous automated
immunoassays, protein binding assays, and in-house LC-MS/MS methods are being …
immunoassays, protein binding assays, and in-house LC-MS/MS methods are being …
The C-3 Epimer of 25-Hydroxyvitamin D3 Is Present in Adult Serum
G Lensmeyer, M Poquette, D Wiebe… - The Journal of Clinical …, 2012 - academic.oup.com
Context: Epimers have identical molecular structure but differ in stereochemical
configuration. It is widely believed that the C-3 epimer of 25-hydroxyvitamin D3 [3-epi-25 …
configuration. It is widely believed that the C-3 epimer of 25-hydroxyvitamin D3 [3-epi-25 …
Analytical measurement of serum 25-OH-vitamin D3, 25-OH-vitamin D2 and their C3-epimers by LC–MS/MS in infant and pediatric specimens
M Yazdanpanah, D Bailey, W Walsh, B Wan, K Adeli - Clinical biochemistry, 2013 - Elsevier
Objectives To develop a simple and sensitive LC–MS/MS procedure for quantification of
serum 25-OH-vitamin D 3 (25-OH-D 3), 25-OH-vitamin D 2 (25-OH-D 2), and their C3 …
serum 25-OH-vitamin D 3 (25-OH-D 3), 25-OH-vitamin D 2 (25-OH-D 2), and their C3 …
C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of …
RJ Singh, RL Taylor, GS Reddy… - The Journal of Clinical …, 2006 - academic.oup.com
Context: We have recently introduced liquid chromatography-tandem mass spectrometry
(LC-MS/MS) for 25-hydroxyvitamin D2 (25OHD2) and 25OHD3 testing. During subsequent …
(LC-MS/MS) for 25-hydroxyvitamin D2 (25OHD2) and 25OHD3 testing. During subsequent …
3-epi-25 hydroxyvitamin D concentrations are not correlated with age in a cohort of infants and adults
FG Strathmann, K Sadilkova, TJ Laha, SE LeSourd… - Clinica chimica acta, 2012 - Elsevier
BACKGROUND: The implementation of mass spectrometry to measure serum 25-
hydroxyvitamin D [25 (OH) D] concentrations has led to concerns regarding the …
hydroxyvitamin D [25 (OH) D] concentrations has led to concerns regarding the …
Full-scan mass spectral evidence for 3-epi-25-hydroxyvitamin D3 in serum of infants and adults
HCM Stepman, A Vanderroost, D Stöckl… - Clinical Chemistry and …, 2011 - degruyter.com
Background: Since the introduction of liquid chromatography-mass spectrometry (LC/MS) for
assessing vitamin D status, it has been shown that the C-3 epimer can account for a …
assessing vitamin D status, it has been shown that the C-3 epimer can account for a …
Fast Separation of 25-Hydroxyvitamin D3 from 3-Epi-25-Hydroxyvitamin D3 in Human Serum by Liquid Chromatography–Tandem Mass Spectrometry: Variable Prevalence of 3 …
JMW van den Ouweland, AM Beijers… - Clinical …, 2011 - academic.oup.com
Liquid chromatography–tandem mass spectrometry (LC-MS/MS) is becoming increasingly
popular for the measurement of 25-hydroxyvitamin D [25 (OH) D] in human serum. A …
popular for the measurement of 25-hydroxyvitamin D [25 (OH) D] in human serum. A …
Assessing vitamin D status: time for a rethink?
GD Carter, KW Phinney - Clinical chemistry, 2014 - academic.oup.com
Vitamin D status is universally assessed by measuring circulating total 25-hydroxyvitamin D
[25 (OH) D] 3, the sum of 25 (OH) D3 and 25 (OH) D2. However, despite the widespread …
[25 (OH) D] 3, the sum of 25 (OH) D3 and 25 (OH) D2. However, despite the widespread …
[HTML][HTML] Vitamin D metabolites: analytical challenges and clinical relevance
N Alonso, S Zelzer, G Eibinger, M Herrmann - Calcified tissue international, 2023 - Springer
Recent research activities have provided new insights in vitamin D metabolism in various
conditions. Furthermore, substantial progress has been made in the analysis of vitamin D …
conditions. Furthermore, substantial progress has been made in the analysis of vitamin D …
Accuracy and clinical implications of seven 25-hydroxyvitamin D methods compared with liquid chromatography–tandem mass spectrometry as a reference
HJ Roth, H Schmidt-Gayk, H Weber… - Annals of clinical …, 2008 - journals.sagepub.com
Background The most reliable assessment of vitamin D status is measurement of plasma 25-
hydroxyvitamin D (25 [OH] D) concentration. High variability in 25 (OH) D measurements …
hydroxyvitamin D (25 [OH] D) concentration. High variability in 25 (OH) D measurements …