The relationship of pain, allodynia and thermal sensation in post-herpetic neuralgia

MC Rowbotham, HL Fields - Brain, 1996 - academic.oup.com
In the syndrome of post-herpetic neuralgia (PHN), the nature of the sensory disturbance and
its relationship both to the severity and cause of the pain is controversial. To address these …

Post-herpetic neuralgia: the relation of pain complaint, sensory disturbance and skin temperature

MC Rowbotham, HL Fields - Pain, 1989 - Elsevier
Twelve otherwise healthy patients with longstanding postherpetic neuralgia (PHN) were
prospectively studied using clinical examination, infrared thermography and response to …

Cutaneous innervation density in the allodynic form of postherpetic neuralgia

MC Rowbotham, G Yosipovitch, MK Connolly… - Neurobiology of …, 1996 - Elsevier
The relationship between deafferentation, sensory function, and pain was explored in 18
subjects with chronic postherpetic neuralgia (PHN). Subjective thresholds for warmth …

Heterogenous patterns of sensory dysfunction in postherpetic neuralgia suggest multiple pathophysiologic mechanisms

M Pappagallo, AL Oaklander… - The Journal of the …, 2000 - pubs.asahq.org
Background Postherpetic neuralgia (PHN) is considered by some investigators to be
predominantly a deafferentation-type central pain syndrome; others suggest that activity of …

Association between pain, central sensitization and anxiety in postherpetic neuralgia

T Schlereth, A Heiland, M Breimhorst… - … journal of pain, 2015 - Wiley Online Library
Background In postherpetic neuralgia (PHN), dorsal root ganglia neurons are damaged.
According to the proposed models, PHN pain might be associated with nociceptive …

Postherpetic neuralgia: irritable nociceptors and deafferentation

HL Fields, M Rowbotham, R Baron - Neurobiology of disease, 1998 - Elsevier
Postherpetic neuralgia (PHN) is a common and often devastatingly painful condition. It is
also one of the most extensively investigated of the neuropathic pains. Patients with PHN …

Somatosensory findings in postherpetic neuralgia.

T Nurmikko, D Bowsher - Journal of Neurology, Neurosurgery & …, 1990 - jnnp.bmj.com
Somatic sensory perception thresholds (warm, cold, hot pain, touch, pinprick, vibration, two-
point discrimination), allodynia and skin temperature were assessed in the affected area of …

Capsaicin evoked pain and allodynia in post-herpetic neuralgia

KL Petersen, HL Fields, J Brennum, P Sandroni… - Pain, 2000 - Elsevier
The hypothesis that the pain and allodynia associated with post-herpetic neuralgia (PHN) is
maintained by a combination of input from preserved primary afferent nociceptors and …

Basal heat pain thresholds predict opioid analgesia in patients with postherpetic neuralgia

RR Edwards, JA Haythornthwaite, P Tella… - The Journal of the …, 2006 - pubs.asahq.org
Background A variety of analgesics have been studied in the treatment of postherpetic
neuralgia, with several medications demonstrating some degree of efficacy. However …

Neurogenic hyperalgesia versus painful hypoalgesia: two distinct mechanisms of neuropathic pain

U Baumgärtner, W Magerl, T Klein, HC Hopf… - Pain, 2002 - Elsevier
Patients with sensory disturbances of painful and non-painful character show distinct
changes in touch and/or pain sensitivity. The patterns of sensory changes were compared to …