[引用][C] Effect of fluconazole on the pharmacokinetics and pharmacodynamics of oral and rectal bromazepam: an application of electroencephalography as the …

大谷康清 - 2002 - ci.nii.ac.jp
CiNii 博士論文 - Effect of fluconazole on the pharmacokinetics and pharmacodynamics of oral
and rectal bromazepam : an application of electroencephalography as the pharmacodynamic …

Effect of fluconazole on the pharmacokinetics and pharmacodynamics of oral and rectal bromazepam: an application of electroencephalography as the …

Y Ohtani, T Kotegawa, K Tsutsumi… - The Journal of …, 2002 - Wiley Online Library
Quantitative analysis of electroencephalography (EEG) is used increasingly to evaluate the
pharmacodynamics of benzodiazepines. The present study aimed to apply the EEG method …

Effect of food on the bioavailability of bromazepam following oral administration in healthy volunteers

J FUJII, N INOTSUME, M NAKANO - Journal of pharmacobio …, 1990 - jstage.jst.go.jp
抄録 The effect of food on the rate and extent of bioavailability of bromazepam was
examined in seven normal volunteers following a single oral dose of 10 mg bromazepam …

Quazepam の薬物動態と薬効に及ぼすitraconazole およびfluconazole の影響

倉成正恵, 小手川勤, 堤喜美子, 今井浩光, 桑谷圭二… - 臨床薬理, 2004 - jstage.jst.go.jp
[目的] QuazePam (QZP) は, ベンゾジアゼピン系の睡眠薬であり, その代謝には cytochrome
P450 (CYP) 3A4 と CYP2C9 の 二つの分子種の関与が報告されている. 本研究では, CYP3A4 の …

Clonazepam の直腸内投与に関する基礎的研究: 家兎による薬物動態学的検討

小林輝明, 石射正英, 黒山政一, 佐川賢一, 朝長文弥… - 北里医学, 1984 - cir.nii.ac.jp
抄録 Clonazepam の坐剤ならびに注腸用溶液の臨床応用が可能であるか否かを検討する第一歩
として, 油脂性基剤, 界面活性剤入り油脂性基剤および水溶性基剤を用いた 3 種の坐剤 …

The influence of diflunisal on the pharmacokinetics of oxazepam.

AM Van Hecken, TB Tjandramaga… - British journal of …, 1985 - Wiley Online Library
Single dose pharmacokinetics of oxazepam, 30 mg, have been studied in six healthy male
volunteers in the absence of diflunisal and during continuous treatment with diflunisal 500 …

Kinetics of clonazepam in relation to electroencephalographic and clinical effects

Y Stahl, A Persson, I Petters, A Rane, K Theorell… - …, 1983 - Wiley Online Library
The aim of this study was to see if the immediate EEG and clinical response to an
intravenous dose of clonazepam was predictive for the effect of oral clonazepam …

Comparative studies on biologic availability and pharmacokinetics of bromazepam in tablets

O von Stetten, KD Rehm, E Fenzl… - Arzneimittel …, 1983 - europepmc.org
Ten male volunteers participated in a randomized crossover trial to compare the
bioavailability of bromazepam (7-bromo-1, 3-dihydro-5-(2-pyridyl)-2H-1, 4-benzodiazepin-2 …

Pharmacokinetic Characteristics of Oral Clonazepam in Korean

정지훈, 유대식, 박준홍, 이석용, 손의동 - YAKHAK HOEJI, 2004 - yakhak.org
In order to determine the bioavailability of clonazepam, an anxiolytic drug, a simple, rapid
and sensitive HPLC analysis was developed in healthy Korean volunteers. The analysis …

Effect of multiple dose omeprazole on the pharmacokinetics of carbamazepine

MUR Naidu, JC Shobha, VK Dixit, A Kumar, TR Kumar… - Drug Investigation, 1994 - Springer
The pharmacokinetics of carbamazepine (CBZ) were studied in 7 patients with duodenal
ulcer both before and after 14 days' treatment with omeprazole (20 mg/day), as this …