We examined the extent of variation of the 3′ region of the Circumsporozoite gene among
Plasmodium falciparum isolates through amplification of a selected DNA fragment followed …

To determine the nature and extent of variation in the T cell sites of the Plasmodium
falciparum circumsporozoite (CS) protein, a candidate antigen in the development of a …

Variation in the immunodominant T cell epitopes Th2R and Th3R of the Plasmodium
falciparum circumsporozoite protein has been analysed from Gambian clinical isolates using …

The circumsporozoite (CS) protein that covers the surface of infectious sporozoites is a
candidate antigen in malaria vaccine development. To determine the extent of B-and T …

Allelic variation in the Plasmodium falciparum circumsporozoite(CS) pro tein gene has been
examined by sequencing the entire gene in IS isolates from an endemic area of Thailand …

Allelic variation in the Plasmodium falciparum circumsporozoite protein (CS) gene has been
determined by sequencing the immunodominant T-cell epitopes, Th2R and Th3R, from 95 …

The complete nucleotide sequence of the cloned circumsporozoite protein gene of the
Plasmodium falciparum Wellcome (West African) isolate has been determined. The …

Genetic analysis of field isolates of Plasmodium falciparum has shown selective
accumulation of point mutations within the immunologically sensitive sites of the …

Identification of T cell antigenic sites is critical for antisporozoite malarial vaccine design.
Here, we present data that define two minimal functional T cell sites present in an …

The design of a subunit vaccine against the malaria parasite relies on the epitopes
recognized by T cells being identified and polymorphisms therein being defined. Here we …