Antibiotic resistance has become a global health problem for humankind. Improper use of
antibiotics resulted in the increasing evolved bacterial resistance to them. There are different …

Bacterial multidrug resistance efflux systems serve an important role in antimicrobial
resistance. Thus, identifying novel and effective efflux pump inhibitors that are safe with no …

Expression of bacterial efflux pump is one of the major causes for developing antibiotic
resistance in a variety of pathogens. Efflux pump inhibitors (EPIs) are potential molecules …

Background Antimicrobial resistance development poses a significant danger to the efficacy
of antibiotics, which were once believed to be the most efficient method for treating infections …

Studies continue every day with the increase in multi-drug resistance in bacteria. In this
study, the effect of potential inhibitors against the efflux pump with natural components in …

Antibacterial and synergy potential of naturally occurring indole alkaloids (IA): 10‐methoxy
tetrahydroalstonine (1), isoreserpiline (2), 10 and 11 demethoxyreserpiline (3), reserpiline …

Efflux pumps are always at the forefront of bacterial multidrug resistance and account for the
failure of antibiotics. The present study explored the potential of 2-(2-Aminophenyl) indole …

Background: Antibiotic-resistant pathogens became a real global threat to human and
animal health. This needs to concentrate the efforts to minimize and control these …

The emergence of antibiotic resistance has led to the search for novel strategies that can
overcome this issue. In this connection, the plant secondary metabolites play a crucial role in …

Background One of the causes of antibiotic resistance is the reduced accumulation of
antibiotics in bacterial cells through pumping out the drugs. Silybin, a key component of the …