Novel regioselective hydroxyl-alkylation of 4, 5-diphenylimidazole-2-thione and a competitive intramolecular ring closure of the S-hydroxyalkyl-imidazoles to imidazo …

ESH El Ashry, N Rashed, LF Awad… - … , and Nucleic Acids, 2007 - Taylor & Francis
Under both conventional method (CM) and microwave (MW) irradiation (MWI) conditions,
alkylation of 4, 5-diphenylimidazole-2-thione (1) with halogeno-alkanols 2 or 5 …

Regioselectivity of the reactions of 4,5‐diphenylimidazole‐2‐thione with 1‐chloro‐2,3‐epoxy‐propane and 1‐bromo‐propene, efficient precursors for imidazo[2,1‐b] …

MR Aouad, NT Rezki… - Journal of Heterocyclic …, 2008 - Wiley Online Library
A solid support under microwave (MW) irradiation without solvent allowed the synthesis of
the 2, 3‐epoxy‐propyl‐thioimidazole 4, regioselectively, and prohibited its cyclization to give …

[PDF][PDF] MAOS versus conventional synthesis of 4, 5-di-and 3, 4, 5-triphenylimidazole-2-thione and their derivatives

ESH El Ashry, N Rashed, LF Awad, E Ramadan… - Arkivoc, 2007 - pdfs.semanticscholar.org
Abstract Microwave-Assisted Organic Synthesis (MAOS) of 4, 5-di-and 3, 4, 5-
triphenylimidazole (1) and (2) has been achieved by reaction of benzoin with ammonium …

Metal‐Free Synthesis of Imidazo[2,1‐b]thiazoles from Thioimidazoles and Ketones Mediated by Selectfluor

J Zhao, Q Xiao, J Chen, J Xu - European Journal of Organic …, 2020 - Wiley Online Library
This paper presents a practical and efficient strategy for the preparation of imidazol [2, 1‐b]‐
thiazoles from thioimidazoles and ketones mediated by Selectfluor. The proposed …

[PDF][PDF] Regioselective reaction of imidazole-2-thiols with N-sulfonylphenyldichloroacetaldimines: en route to novel sulfonylaminosubstituted imidazo [2, 1-b] thiazoles …

VY Serykh, AR Kaliev, IA Ushakov, TN Borodina… - Arkivoc, 2018 - arkat-usa.org
Abstract The reaction of N-(2, 2-dichloro-2-phenylethylidene) arenesulfonamides with 2-
mercaptoimidazoles affords N-(2-phenylimidazo [2, 1-b][1, 3] thiazol-3-yl) …

High throughput synthesis of 2, 3, 6-trisubstituted-5, 6-dihydroimidazo [2, 1-b] thiazole derivatives

Y Li, M Giulianotti, RA Houghten - Tetrahedron letters, 2011 - Elsevier
A facile approach to the synthesis of 2, 3, 6-trisubstituted-5, 6-dihydroimidazo [2, 1-b]
thiazole was reported. A resin bound cyclic thiourea was formed by the treatment of a resin …

Approach for 2-(arylthio) imidazoles and imidazo [2, 1-b] thiazoles from imidazo [2, 1-b][1, 3, 4] thiadiazoles by ring-opening and-reconstruction

B Shi, Z Zhu, YS Zhu, D Zhou, J Wang… - Organic & Biomolecular …, 2016 - pubs.rsc.org
A highly efficient one-pot synthesis of imidazo [2, 1-b] thiazole derivatives has been
developed and proceeds via a ring-opening and ring-closing reconstruction of imidazo [2, 1 …

A thorough study on the reaction of DMAD with 1-arylaminoimidazole-2-thiones. Expeditious synthesis of imidazo [2, 1-b][1, 3] thiazoles through a novel arylamino …

C Neochoritis, N Eleftheriadis, CA Tsoleridis… - Tetrahedron, 2010 - Elsevier
Upon reaction of 1-arylamino-imidazole-2-thiones 1 with dimethyl acetylenedicarboxylate
(DMAD) in the presence of 2.2 equiv of sodium hydride, imidazothiazoles 4 were exclusively …

1-Arylaminoimidazole-2-thiones as intermediates in the synthesis of imidazo [2, 1-b][1, 3, 4] thiadiazines

C Neochoritis, CA Tsoleridis… - Tetrahedron, 2008 - Elsevier
The synthesis of the hitherto unknown imidazo [2, 1-b][1, 3, 4] thiadiazines 7 in good to very
good yields (up to 77%) by using suitable imidazole-2-thione precursors 1 has been …

Synthesis of new functionalized imidazo[2,1‐b]thiazoles and thiazolo[3,2‐a]pyrimidines

L Peterlin‐Mašič, M Malešič, M Breznik… - Journal of …, 2000 - Wiley Online Library
Oxo‐5H‐[1, 3] thiazolo [3, 2‐a] pyrimidine‐6‐carboxylic acid (4), and 6‐methylimidazo [2, 1‐
b] thiazole‐5‐carboxylic acid (17) were reacted with amines 6a‐i by the reaction with oxalyl …