The incidence and prevalence of metabolic syndrome has steadily increased worldwide. As
a major risk factor for various diseases, metabolic syndrome has come into focus in recent …

Roemerine is a naturally occurring aporphine alkaloid. In this study, we screened a
conformer library of Food and Drug Administration (FDA)-approved drugs to identify similar …

Background Cancer is the most common cause of death and is still a serious public health
problem. Alkaloids, a class of bioactive compounds widely diffused in plants, especially …

Aporphine alkaloids from the leaves of Nelumbo nucifera Gaertn are substances of great
interest because of their important pharmacological activities, particularly anti-diabetic, anti …

Aporphine alkaloids embedded in 4H-dibenzo [de, g] quinoline four-ring structures belong to
one of the largest subclasses of isoquinoline alkaloids. Aporphine is a privileged scaffold in …

The incidence of complex noncommunicable diseases has strongly increased over the last
several decades in the US, Europe and other parts of the world that have adopted a western …

Plant and folk medicine represent nowadays a source of either new therapeutic substances
or substrates for drug synthesis. One such promising group for possible further exploitation …

Xylopia aethiopica has been widely utilized as food condiments in West African countries, as
well as traditional medicine for diabetes, but the responsible components remain unknown …

Albiflorin (AF) is a small molecule (MW 481) isolated from Paeoniae radix, a plant used as a
remedy for various conditions with pathogenesis shared by metabolic diseases. Reported …

Obesity, is an increasingly global public health problem associated complications. However,
the proven anti-obesity agents are inefficient with adverse side effects; hence attention is …