[HTML][HTML] Association of allostatic load with brain structure and cognitive ability in later life

T Booth, NA Royle, J Corley, AJ Gow… - Neurobiology of …, 2015 - Elsevier
Allostatic load (AL) has been proposed as a general framework for understanding the
cumulative effects of life stress on individuals. Despite growing interest in AL, limited …

Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging

TE Seeman, BS McEwen, JW Rowe… - Stress and the …, 2013 - taylorfrancis.com
Allostatic load (AL) has been proposed as a new conceptualization of cumulative biological
burden exacted on the body through attempts to adapt to life's demands. Using a …

The association between allostatic load and cognitive function: A systematic and meta-analytic review

D D'Amico, ME Amestoy, AJ Fiocco - Psychoneuroendocrinology, 2020 - Elsevier
Previous research suggests that high allostatic load (AL), a biological indicator of
physiological dysregulation due to chronic stress, is associated with poor cognitive …

Depression interacts with allostatic load to predict cognitive decline in middle age

G Perlman, H Cogo-Moreira, CY Wu… - …, 2022 - Elsevier
Background Allostatic load (AL) indicates the cumulative impact of stress on homeostatic
mechanisms. Depression and AL have been associated with cognitive deficits, but it is …

Allostatic load associations to acute, 3-year and 6-year prospective depressive symptoms in healthy older adults

RP Juster, MF Marin, S Sindi, NPV Nair, YK Ng… - Physiology & …, 2011 - Elsevier
Allostatic load represents the strain that chronic stress exerts on interconnected biological
systems. Associated algorithms are related to numerous deleterious physical outcomes in …

Allostatic load as a predictor of grey matter volume and white matter integrity in old age: The Whitehall II MRI study

E Zsoldos, N Filippini, A Mahmood, CE Mackay… - Scientific reports, 2018 - nature.com
The allostatic load index quantifies the cumulative multisystem physiological response to
chronic everyday stress, and includes cardiovascular, metabolic and inflammatory …

The mediating role of allostatic load in the relationship between early life adversity and cognitive function across the adult lifespan

D D'Amico, ME Amestoy, AJ Fiocco - Psychoneuroendocrinology, 2022 - Elsevier
Early life adversity is consequential for poor cognitive health in mid to late-life. Early life
adversity is associated with higher allostatic load, a biological indicator of physiological …

[HTML][HTML] Allostatic load is linked to cortical thickness changes depending on body-weight status

J Ottino-González, MA Jurado… - Frontiers in Human …, 2017 - frontiersin.org
Objective: Overweight (body mass index or BMI≥ 25 kg/m2) and stress interact with each
other in complex ways. Overweight promotes chronic low-inflammation states, while stress is …

Allostatic load as a predictor of functional decline: MacArthur studies of successful aging

AS Karlamangla, BH Singer, BS McEwen… - Journal of clinical …, 2002 - Elsevier
Allostatic load has been proposed as a cumulative measure of dysregulation across multiple
physiological systems, and has been postulated to impact health risks. In the allostatic load …

[HTML][HTML] The association between allostatic load and brain: A systematic review

M Lenart-Bugla, D Szcześniak, B Bugla… - …, 2022 - Elsevier
Allostatic load (AL) refers to prolonged dysregulation related to chronic stress that affects
brain regions such as the hippocampus, amygdala, and prefrontal cortex (PFC). Higher …