Endogenous opioids, and in particular μ-opioid receptors, have been linked to hedonic and
rewarding mechanisms engaged during palatable food intake. The aim of this study was to …

Endogenous opioids and μ‐opioid receptors have been linked to hedonic and rewarding
aspects of palatable food intake. The authors examined the safety, pharmacokinetic, and …

Opioids are important in reward processes leading to addictive behavior such as self-
administration of opioids and other drugs of abuse including nicotine and alcohol. Opioids …

Endogenous opioids and µ-opioid receptors (MORs) have long been implicated in the
mechanism of appetite control and, in particular, hedonic processes associated with food …

The opioid system is implicated in the hedonic and motivational processing of food, and in
binge eating, a behaviour strongly linked to obesity. The aim of this study was to evaluate …

Various aspects of feeding behavior (eg consumption, motivation and anticipation) are
regulated by homeostatic and hedonic systems, and are modulated by dopaminergic and …

BACKGROUND: Binge eating is associated with obesity and has been conceptualized as
“food addiction.” However, this view has received only inconsistent support in humans, and …

Mu opioid (MOP) agonists acting in the nucleus accumbens (NAcc) robustly enhance
consumption of palatable foods. In addition, the effect on consumption of palatable foods …

μ-Opioid receptor (MOR) agonism induces palatable food consumption principally through
modulation of the rewarding properties of food. N-{[3, 5-difluoro-3′-(1 H-1, 2, 4-triazol-3-yl) …

Rationale Translational research implicates the mu opioid neurochemical system in hedonic
processing, but its role in dissociable high-level cognitive functions is not well understood …