The rifamycin antibacterials, rifampicin (rifampin), rifabutin and rifapentine, are uniquely
potent in the treatment of patients with tuberculosis and chronic staphylococcal infections …

The antituberculosis drug rifampicin (rifampin) induces a number of drug-metabolising
enzymes, having the greatest effects on the expression of cytochrome P450 (CYP) 3A4 in …

The World Health Organization encourages the use of fixed dose combinations (FDCs) of
rifampicin (RMP) and isoniazid together with pyrazinamide or pyrazinamide plus ethambutol …

Rifampicin, an antituberculosis drug, is usually administered for 4 to 12 months with other
antituberculosis drugs or medications from other classes. A potential for drug interactions …

Rifampin* is a semisynthetic antibiotic derived from the natural product rifamycin B, which is
produced by a strain of Nocardia (= Streptomyces) mediterranea together with four other …

The activities of rifapentine and rifampin against Mycobacterium tuberculosis residing in
human monocyte-derived macrophages were determined. The MICs and MBCs of …

Rationale: Comparison of the early bactericidal activity (EBA) of rifapentine and its
pharmacokinetics with those of rifampin to determine the cause of poor clinical response …

The unique pharmacokinetic properties of rifampin in humans are discussed in this review.
These properties can be better understood by assuming the existence of two …

After oral administration on an empty stomach, the absorption of rifampicin (rifampin) is rapid
and practically complete. With a single 600mg dose, peak serum concentrations of the order …

The introduction of rifampicin (rifampin) into tuberculosis (TB) treatment five decades ago
was critical for shortening the treatment duration for patients with pulmonary TB to 6 months …