[Objective]: To determine genome-wide methylation profiles of bone from patients with hip
osteoarthritis (OA) and those with osteoporotic (OP) hip fractures.[Methods]: Trabecular bone …

Objective To determine genome‐wide methylation profiles of bone from patients with hip
osteoarthritis (OA) and those with osteoporotic (OP) hip fractures. Methods Trabecular bone …

Background Researches indicate that epigenetics was involved in osteoarthritis (OA). The
purpose of this study was to describe the alterations of DNA methylation in hip and knee OA …

DNA methylation is an important epigenetic modification that contributes to the lineage
commitment and specific functions of different cell types. In this study, we compared …

Background Evidence suggests that epigenetics plays a role in osteoarthrits (OA). The aim
of the study was to describethe genome wide DNA methylation changes in hip and knee OA …

ABSTRACT DNA methylation affects expression of associated genes and may contribute to
the missing genetic effects from genome-wide association studies of osteoporosis. To …

Epigenetic mechanisms regulate gene expression and are heritable through cell divisions
even though they do not involve modifications in the gene sequence. They include …

Objective To perform a genome‐wide DNA methylation study to identify differential DNA
methylation patterns in subchondral bone underlying eroded and intact cartilage from …

Background Osteoarthritis is a chronic musculoskeletal disease characterized by age-
related gradual thinning and a high risk in females. Recent studies have shown that DNA …

The aim of this study was to investigate the relationship between osteoporosis and
osteoarthritis by analyzing the DNA methylation in osteoporosis and osteoarthritis. The …