Quinolizidine alkaloids derivatives from Sophora alopecuroides Linn: Bioactivities, structure-activity relationships and preliminary molecular mechanisms

Y Li, G Wang, J Liu, L Ouyang - European Journal of Medicinal Chemistry, 2020 - Elsevier
Quinolizidine alkaloids, as essential active ingredients extracted from Sophora
alopecuroides Linn, have been well concerned in the past several decades owing to the …

Quinolizidine alkaloids from Sophora tonkinensis and their anti-inflammatory activities

LJ He, JS Liu, D Luo, YR Zheng, YB Zhang, GC Wang… - Fitoterapia, 2019 - Elsevier
Two new quinolizidine-based alkaloids (2 and 12), along with ten known ones (1, 3–11)
were isolated from the roots of S. tonkinensis. Their structures were determined by …

In Vitro Anti‐Tumour Activities of Quinolizidine Alkaloids Derived from Sophora Flavescens Ait

Z Lin, CF Huang, XS Liu, J Jiang - Basic & clinical …, 2011 - Wiley Online Library
The dry root of Sophora flavescens Ait.(SF) has long been used in a variety of Chinese
herbal formulations to treat patients with cancer. Alkaloids are commonly known to present …

Quinolizidine Alkaloids from Sophora alopecuroides

MI Choudhary, K Parvez, A Ahmed… - Journal of natural …, 2000 - ACS Publications
A new matrine-type alkaloid, 7α-hydroxysophoramine (1), was isolated from the aerial parts
of Sophora alopecuroides together with eight known alkaloids, 12β-hydroxysophocarpine …

Comparative analysis of quinolizidine alkaloids from different parts of Sophora alopecuroides seeds by UPLC–MS/MS

H Wang, S Guo, D Qian, Y Qian, J Duan - Journal of pharmaceutical and …, 2012 - Elsevier
The seeds of Sophora alopecuroides L. have been utilized as a crude drug in China for
thousands of years. Quinolizidine alkaloids are the main bioactive components of this plant …

Naturally occurring plant isoquinoline N-oxide alkaloids: Their pharmacological and SAR activities

VM Dembitsky, TA Gloriozova, VV Poroikov - Phytomedicine, 2015 - Elsevier
The present review describes research on novel natural isoquinoline alkaloids and their N-
oxides isolated from different plant species. More than 200 biological active compounds …

Sophora alopecuroides L.: An ethnopharmacological, phytochemical, and pharmacological review

R Wang, X Deng, Q Gao, X Wu, L Han, X Gao… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Sophora alopecuroides L., which is called Kudouzi in
China, is a medicinal plant distributed in Western and Central Asia, especially in China, and …

Biologically active quinoline and quinazoline alkaloids part II

XF Shang, SL Morris‐Natschke… - Medicinal research …, 2018 - Wiley Online Library
To follow‐up on our prior Part I review, this Part II review summarizes and provides updated
literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009 …

Chemical diversity, biological activities and Traditional uses of and important Chinese herb Sophora

P Sun, W Zhao, Q Wang, L Chen, K Sun, Z Zhan… - Phytomedicine, 2022 - Elsevier
Abstract Background Sophora flavescens Aiton (SF), also known as Kushen (Chinese: 苦参),
has been an important species in Chinese medicine since the Qin and Han dynasties. It is …

Quinolizidine Alkaloids with Antiviral and Insecticidal Activities from the Seeds of Sophora tonkinensis Gagnep

J Zou, L Zhao, P Yi, Q An, L He, Y Li… - Journal of Agricultural …, 2020 - ACS Publications
The discovery of novel, effective, and botanical pesticides is one of the main strategies for
modern plant protection and insect pest control. During the search for novel botanical …