Peripheral neuropathy is one of the main side-effects of novel therapeutics used in
oncohematological diseases, but the molecular basis underlying its development and …

Bortezomib-induced peripheral neuropathy (BiPN) occurs in approximately 40% of patients
with multiple myeloma. The induction of severe neuropathy entails the dose reduction or …

Although microRNAs (miRNAs or miRs) have been studied in the peripheral nervous
system, their function in Schwann cells remains elusive. In this study, we performed a …

Neuroblastoma is a pediatric cancer of the developing sympathetic nervous system. High
risk neuroblastoma patients typically undergo an initial remission in response to treatment …

Objective To analyze the changes in downstream genes, signaling pathways, and proteins
based on the difference of microRNA (miRNA) expression in neuroblastoma (NB). Methods …

Bortezomib is an anti-tumor agent, which inhibits 26S proteasome degrading ubiquitinated
proteins. While apoptotic transcription-associated activation in response to bortezomib has …

Background: MicroRNAs (miRNAs) are small noncoding RNAs whose function as
modulators of gene expression is crucial for the proper control of cell growth. Although many …

Neural stem cells (NSCs) possess self‐renewal and multilineage differentiation ability, thus
are considered to be a potential source for cell replacement therapy of many nervous system …

MicroRNAs are novel class of small non-coding RNAs that target and silence various genes
across diverse signalling pathways comprising key physiological networks. Despite an …

To investigate the expressional alternation of microRNAs (miRNA) during the malignant
transformation and development of human glioma, we measured miRNA expression profile …