Biological effects of airborne fine particulate matter (PM2. 5) exposure on pulmonary immune system

T Wei, M Tang - Environmental toxicology and pharmacology, 2018 - Elsevier
Airborne fine particulate matter (PM 2.5) attracts more and more attention due to its
environmental effects. The immune system appears to be a most sensitive target organ for …

[HTML][HTML] PM2. 5 exposure in the respiratory system induces distinct inflammatory signaling in the lung and the liver of mice

S Jeong, SA Park, I Park, P Kim, NH Cho… - Journal of immunology …, 2019 - hindawi.com
Fine particulate matter 2.5 (PM2. 5) is a harmful air pollutant currently threatening public
health. Although many studies have been performed on the general negative effects of PM2 …

Particulate matter exposure induces the autophagy of macrophages via oxidative stress-mediated PI3K/AKT/mTOR pathway

R Su, X Jin, W Zhang, Z Li, X Liu, J Ren - Chemosphere, 2017 - Elsevier
Many epidemiological investigations have consistently demonstrated the immunotoxicity of
fine particulate matter (PM 2.5), but the underlying molecular mechanism remains unclear …

PM2.5 Exposure Induces Inflammatory Response in Macrophages via the TLR4/COX-2/NF-κB Pathway

H Fu, X Liu, W Li, Y Zu, F Zhou, Q Shou, Z Ding - Inflammation, 2020 - Springer
Fine particulate matter with an aerodynamic diameter less than 2.5 μm (PM2. 5) is a serious
air pollutant associated with health problems. Macrophages play an important role in the …

Exposure to particulate matter 2.5 (PM2. 5) induced macrophage-dependent inflammation, characterized by increased Th1/Th17 cytokine secretion and cytotoxicity

QY Ma, DY Huang, HJ Zhang, S Wang… - International …, 2017 - Elsevier
Particulate matter PM2. 5 is a class of airborne particles and droplets with sustained high
levels in many developing countries. Epidemiological studies have shown the association …

Particulate matter (PM10) induces in vitro activation of human neutrophils, and lung histopathological alterations in a mouse model

A Valderrama, P Ortiz-Hernández, JM Agraz-Cibrián… - Scientific Reports, 2022 - nature.com
The epidemiological association between exposure to particulate matter (PM10) and various
respiratory and cardiovascular problems is well known, but the mechanisms driving these …

Effects of ambient PM2.5 on pathological injury, inflammation, oxidative stress, metabolic enzyme activity, and expression of c-fos and c-jun in lungs of rats

R Li, X Kou, L Xie, F Cheng, H Geng - Environmental Science and …, 2015 - Springer
Abstract Fine particulate matter (PM 2.5) exposure is associated with morbidity and mortality
induced by respiratory diseases and increases the lung cancer risk. However, the …

[HTML][HTML] The Impact of PM2.5 on the Host Defense of Respiratory System

L Yang, C Li, X Tang - Frontiers in cell and developmental biology, 2020 - frontiersin.org
The harm of fine particulate matter (PM2. 5) to public health is the focus of attention around
the world. The Global Burden of Disease (GBD) Study 2015 ranked PM2. 5 as the fifth …

Biological effect of PM10 on airway epithelium-focus on obstructive lung diseases

P Misiukiewicz-Stepien, M Paplinska-Goryca - Clinical immunology, 2021 - Elsevier
Recently, a continuous increase in environmental pollution has been observed. Despite
wide-scale efforts to reduce air pollutant emissions, the problem is still relevant. Exposure to …

Effects on IL-1β signaling activation induced by water and organic extracts of fine particulate matter (PM2. 5) in vitro

F Xu, X Qiu, X Hu, Y Shang, M Pardo, Y Fang… - Environmental …, 2018 - Elsevier
Abstract Fine particulate matter (PM 2.5) air pollution poses a major risk to human health
worldwide, and absorbed chemicals play a key role in determining the toxicity of PM 2.5 …