[HTML][HTML] Long-acting bronchodilators improve exercise capacity in COPD patients: a systematic review and meta-analysis

F Di Marco, G Sotgiu, P Santus, DE O'Donnell… - Respiratory …, 2018 - Springer
Background We carried out a systematic review and meta-analysis with the aim to evaluate
the efficacy of long-acting bronchodilators on exercise capacity in COPD patients. Methods …

[HTML][HTML] Impact of LABA/LAMA combination on exercise endurance and lung hyperinflation in COPD: a pair-wise and network meta-analysis

L Calzetta, J Ora, F Cavalli, P Rogliani… - Respiratory …, 2017 - Elsevier
Background The ability to exercise is an important clinical outcome in COPD, and the
improvement in exercise capacity is recognized to be an important goal in the management …

[HTML][HTML] Walking exercise response to bronchodilation in mild COPD: a randomized trial

P Gagnon, D Saey, S Provencher, J Milot… - Respiratory …, 2012 - Elsevier
RATIONALE: Patients with mild chronic obstructive pulmonary disease (COPD) present
abnormal ventilatory mechanics during exercise and may require bronchodilator therapy …

Assessment of bronchodilator efficacy in symptomatic COPD: is spirometry useful?

DE O'Donnell - Chest, 2000 - Elsevier
Bronchodilator therapy in COPD is deemed successful if it improves ventilatory mechanics to
a degree where effective symptom alleviation and increased exercise capacity are achieved …

[HTML][HTML] Can bronchodilators improve exercise tolerance in COPD patients without dynamic hyperinflation?

MEA Scuarcialupi, DC Berton, PK Cordoni… - Jornal Brasileiro de …, 2014 - SciELO Brasil
OBJECTIVE: To investigate the modulatory effects that dynamic hyperinflation (DH), defined
as a reduction in inspiratory capacity (IC), has on exercise tolerance after bronchodilator in …

A systematic review of the effects of bronchodilators on exercise capacity in patients with COPD

JJW Liesker, PJ Wijkstra, NHT Ten Hacken, GH Koëter… - Chest, 2002 - Elsevier
One of the major goals of bronchodilator therapy in patients with COPD is to decrease
airflow limitation in the airways and, as a consequence, improve dyspnea and exercise …

Relationship between exercise endurance and static hyperinflation in a post hoc analysis of two clinical trials in patients with COPD

S Singh, F Maltais, L Tombs, WA Fahy… - … Journal of Chronic …, 2018 - Taylor & Francis
Background Lung hyperinflation and exercise intolerance are hallmarks of chronic
obstructive pulmonary disease (COPD). However, their relationship remains uncertain. A …

A comparison of the effects of salbutamol and ipratropium bromide on exercise endurance in patients with COPD

T Oga, K Nishimura, M Tsukino, S Sato, T Hajiro… - Chest, 2003 - Elsevier
Study objective Inhaled bronchodilators are the first-line pharmacotherapy against COPD.
The purpose of the present study was to investigate the effects of β 2-agonists and …

[HTML][HTML] Effect of combination treatment on lung volumes and exercise endurance time in COPD

H Magnussen, P Paggiaro, H Schmidt, S Kesten… - Respiratory …, 2012 - Elsevier
BACKGROUND: Data comparing two bronchodilators vs. one bronchodilator plus inhaled
corticosteroid (ICS) on hyperinflation and exercise endurance in chronic obstructive …

Long-acting bronchodilators in COPD: where are we now and where are we going?

M Cazzola, C Page - Breathe, 2014 - Eur Respiratory Soc
Educational aims To discuss fundamental questions relating to the use of bronchodilators
that can lead to an optimisation of their utilisation. To describe new bronchodilators that …