[HTML][HTML] A broad and potent H1-specific human monoclonal antibody produced in plants prevents influenza virus infection and transmission in guinea pigs
Although seasonal influenza vaccines block most predominant influenza types and
subtypes, humans still remain vulnerable to waves of seasonal and new potential pandemic …
subtypes, humans still remain vulnerable to waves of seasonal and new potential pandemic …
[HTML][HTML] Human monoclonal antibodies neutralizing influenza virus A/H1N1pdm09 and seasonal A/H1N1 strains–Distinct Ig gene repertoires with a similar action …
S Hiroi, M Kuhara, Y Kishi, K Ono, S Matsuzawa… - Immunobiology, 2018 - Elsevier
Influenza virus causes acute respiratory infection in humans, and is a major public health
concern globally. Antibodies play a central role in host protection against influenza virus. We …
concern globally. Antibodies play a central role in host protection against influenza virus. We …
[HTML][HTML] A highly potent and broadly neutralizing H1 influenza-specific human monoclonal antibody
A Nogales, MS Piepenbrink, J Wang, S Ortega… - Scientific reports, 2018 - nature.com
Influenza's propensity for antigenic drift and shift, and to elicit predominantly strain specific
antibodies (Abs) leaves humanity susceptible to waves of new strains with pandemic …
antibodies (Abs) leaves humanity susceptible to waves of new strains with pandemic …
[HTML][HTML] Prophylactic and therapeutic efficacy of avian antibodies against influenza virus H5N1 and H1N1 in mice
HH Nguyen, TM Tumpey, HJ Park, YH Byun, LD Tran… - PloS one, 2010 - journals.plos.org
Background Pandemic influenza poses a serious threat to global health and the world
economy. While vaccines are currently under development, passive immunization could …
economy. While vaccines are currently under development, passive immunization could …
Human monoclonal antibodies derived from a patient infected with 2009 pandemic influenza A virus broadly cross-neutralize group 1 influenza viruses
Y Pan, T Sasaki, R Kubota-Koketsu, Y Inoue… - Biochemical and …, 2014 - Elsevier
Influenza viruses are a continuous threat to human public health because of their ability to
evolve rapidly through genetic drift and reassortment. Three human monoclonal antibodies …
evolve rapidly through genetic drift and reassortment. Three human monoclonal antibodies …
Human single-chain antibodies that neutralize homologous and heterologous strains and clades of influenza A virus subtype H5N1
S Maneewatch, J Thanongsaksrikul… - Antiviral …, 2009 - journals.sagepub.com
Background Human antibodies that interfere with the biological activity of haemagglutinins
(HAs) of influenza viruses have high potential as an antiviral agent. Methods Human single …
(HAs) of influenza viruses have high potential as an antiviral agent. Methods Human single …
In Vitro Neutralization Is Not Predictive of Prophylactic Efficacy of Broadly Neutralizing Monoclonal Antibodies CR6261 and CR9114 against Lethal H2 Influenza Virus …
TC Sutton, EW Lamirande, KW Bock, IN Moore… - Journal of …, 2017 - Am Soc Microbiol
Influenza viruses of the H1N1, H2N2, and H3N2 subtypes have caused previous
pandemics. H2 influenza viruses represent a pandemic threat due to continued circulation in …
pandemics. H2 influenza viruses represent a pandemic threat due to continued circulation in …
Broadly reactive human monoclonal antibodies elicited following pandemic H1N1 influenza virus exposure protect mice against highly pathogenic H5N1 challenge
R Nachbagauer, D Shore, H Yang, SK Johnson… - Journal of …, 2018 - Am Soc Microbiol
Broadly cross-reactive antibodies (Abs) that recognize conserved epitopes within the
influenza virus hemagglutinin (HA) stalk domain are of particular interest for their potential …
influenza virus hemagglutinin (HA) stalk domain are of particular interest for their potential …
[HTML][HTML] Identification of broad-spectrum neutralizing antibodies against influenza A virus and evaluation of their prophylactic efficacy in mice
S Son, SB Ahn, G Kim, Y Jang, C Ko, M Kim, SJ Kim - Antiviral Research, 2023 - Elsevier
Influenza A virus continuously infects humans and the antigenic shifts of this respiratory virus
enable it to cross the species barrier, threatening public health with the risk of pandemics …
enable it to cross the species barrier, threatening public health with the risk of pandemics …
Human monoclonal antibody derived from transchromosomic cattle neutralizes multiple H1 clades of influenza A virus by recognizing a novel conformational epitope …
Influenza remains a global health risk and challenge. Currently, neuraminidase (NA)
inhibitors are extensively used to treat influenza, but their efficacy is compromised by the …
inhibitors are extensively used to treat influenza, but their efficacy is compromised by the …