Attention-deficit hyperactivity disorder may be associated with decreased central brain-derived neurotrophic factor activity: clinical and therapeutic implications

SJ Tsai - Medical hypotheses, 2007 - Elsevier
Attention-deficit hyperactivity disorder (ADHD) is a common childhood psychiatric disorder.
Despite intensive research efforts, the aetiology of ADHD remains unknown. Current …

Serum brain-derived neurotrophic factor (BDNF) levels in attention deficit–hyperactivity disorder (ADHD)

C Scassellati, R Zanardini, A Tiberti, M Pezzani… - European child & …, 2014 - Springer
It has been proposed that the neurotrophin brain-derived neurotrophic factor (BDNF) may be
involved in attention deficit–hyperactivity disorder (ADHD) etiopathogenesis. Alterations in …

Increased levels of plasma brain-derived neurotrophic factor (BDNF) in children with attention deficit-hyperactivity disorder (ADHD)

SH Shim, Y Hwangbo, YJ Kwon, HY Jeong… - Progress in Neuro …, 2008 - Elsevier
BACKGROUND: Recent reports have suggested a pathophysiological role of brain-derived
neurotrophic factor (BDNF) in attention deficit-hyperactivity disorder (ADHD). We evaluated …

Attention-deficit hyperactivity disorder and brain-derived neurotrophic factor: a speculative hypothesis

SJ Tsai - Medical Hypotheses, 2003 - Elsevier
Brain-derived neurotrophic factor (BDNF) is important for normal neuronal development.
Attention-deficit hyperactivity disorder (ADHD), a childhood-onset neurodevelopmental …

Decreased serum levels of brain-derived neurotrophic factor in adults with attention-deficit hyperactivity disorder

M Corominas-Roso, JA Ramos-Quiroga… - International Journal …, 2013 - academic.oup.com
It has been hypothesized that brain-derived neurotrophic factor (BDNF) is involved in the
pathogenesis of attention-deficit hyperactivity disorder (ADHD), although experimental data …

Serum brain-derived neurotrophic factor levels in treatment-naïve boys with attention-deficit/hyperactivity disorder treated with methylphenidate: an 8-week …

AP Akay, H Resmi, SA Güney, HÖ Erkuran… - European child & …, 2018 - Springer
Brain-derived neurotrophic factor (BDNF) is an important neurotrophin in the brain that
modulates dopaminergic neurons. In this study, we aimed to investigate the changes in …

Role of neurotrophic factors in attention deficit hyperactivity disorder

SJ Tsai - Cytokine & growth factor reviews, 2017 - Elsevier
Neurotrophins (NTs), a family of proteins including nerve growth factor, brain-derived
neurotrophic factor (BDNF), neurotrophin-3, and neurotrophin-4, are essential for neural …

Rare DNA variants in the brain-derived neurotrophic factor gene increase risk for attention-deficit hyperactivity disorder: a next-generation sequencing study

Z Hawi, TDR Cummins, J Tong, M Arcos-Burgos… - Molecular …, 2017 - nature.com
Attention-deficit hyperactivity disorder (ADHD) is a prevalent and highly heritable disorder of
childhood with negative lifetime outcomes. Although candidate gene and genome-wide …

BDNF concentrations and daily fluctuations differ among ADHD children and respond differently to methylphenidate with no relationship with depressive …

I Cubero-Millán, MJ Ruiz-Ramos… - …, 2017 - Springer
Rationale Brain-derived neurotrophic factor (BDNF) enhances the growth and maintenance
of several monoamine neuronal systems, serves as a neurotransmitter modulator and …

Changes in plasma Brain-derived neurotrophic factor (BDNF) levels induced by methylphenidate in children with Attention deficit–hyperactivity disorder (ADHD)

A Amiri, GT Parizi, M Kousha, F Saadat… - Progress in Neuro …, 2013 - Elsevier
Objectives It has been suggested that BDNF may play a role in the pathogenesis of ADHD.
Our aim is to determine whether methylphenidate can induce changes in plasma BDNF …