The importance of pulmonary surfactant in maintaining normal lung function, and the
observations that alterations in endogenous surfactant contribute to the lung dysfunction …

Objectives To outline both the preclinical and clinical data demonstrating surfactant
alterations in acute lung injury, which provide the rationale for testing exogenous surfactant …

Surfactant therapy for acute lung injury/acute respiratory d... : Current Opinion in Critical
Care Surfactant therapy for acute lung injury/acute respiratory distress syndrome : Current …

Surfactant dysfunction constitutes an important element in the complex pathophysiology of
acute respiratory distress syndrome (ARDS). In this disease, surfactant may become …

▪ Abstract A number of conditions, such as pneumonia, trauma, or systemic sepsis arising
from the gut, may result in the acute respiratory distress syndrome (ARDS). Because of its …

Acute respiratory distress syndrome (ARDS) is often characterized by reduced lung
compliance, which suggests dysfunction of the endogenous surfactant system. The …

The acute respiratory distress syndrome (ARDS) is a frequent, life-threatening disease in
which a marked increase in alveolar surface tension has been repeatedly observed. It is …

This chapter examines exogenous surfactant therapy and its utility in miti-gating clinical
acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS). Extensive …

Background. Patients with acute respiratory distress syndrome (ARDS) have a deficiency of
surfactant. Surfactant replacement improves physiologic function in such patients, and …

Acute lung injury and acute respiratory distress syndrome (ARDS) are characterised by
severe hypoxemic respiratory failure and poor lung compliance. Despite advances in clinical …