Rationale Dysregulation of dopaminergic neurotransmission, specifically altered reward
processing assessed via the reward anticipation in the MID task, plays a central role in the …

The dopaminergic mechanisms that control reward-motivated behavior are the subject of
intense study, but it is yet unclear how, in humans, neural activity in mesolimbic reward …

The dopaminergic mechanisms that control reward-motivated behavior are the subject of
intense study, but it is yet unclear how, in humans, neural activity in mesolimbic reward …

Reward related behaviour is linked to dopaminergic neurotransmission. Our aim was to gain
insight into dopaminergic involvement in the human reward system. Combining functional …

Background Anhedonia and other deficits in reward-and motivation-related processing in
psychiatric patients, including patients with major depressive disorder (MDD), represent a …

Rationale Olanzapine is a neuroleptic drug widely prescribed to treat schizophrenia and
bipolar disorder. Although it is long known that modulation of the dopamine system is a …

The mesolimbic dopaminergic reward system is responsible for the negative affective
symptomatology of schizophrenia, which may be related to a low dopamine tonus within the …

Functional neuroimaging (fMRI) studies show activation in mesolimbic circuitry in tasks
involving reward processing, like the Monetary Incentive Delay Task (MIDT). In voltammetry …

In the research domain framework (RDoC), dysfunctional reward expectation has been
proposed to be a cross-diagnostic domain in psychiatry, which may contribute to symptoms …

Transmission of reward signals is a function of dopamine, a neurotransmitter known to be
involved in the mechanism of psychosis. Using functional magnetic resonance imaging …