Meiotic drive in house mice: mechanisms, consequences, and insights for human biology

UP Arora, BL Dumont - Chromosome Research, 2022 - Springer
Meiotic drive occurs when one allele at a heterozygous site cheats its way into a
disproportionate share of functional gametes, violating Mendel's law of equal segregation …

[HTML][HTML] When it comes to genetics, cheaters do prosper

SL Hanlon, AM Larracuente - Chromosome Research, 2022 - Springer
Though most genetic elements abide by these laws, others routinely break them to increase
their chances of being passed on to the next generation. This unlawful behavior by selfish …

Drive and sperm: the evolution and genetics of male meiotic drive

D Presgraves - Sperm biology, 2009 - Elsevier
Publisher Summary Some selfish genetic elements in eukaryotic genomes have been
harnessed to perform essential functions for their hosts, whereas others have gained …

[HTML][HTML] Meiotic drive changes sperm precedence patterns in house mice: potential for male alternative mating tactics?

A Sutter, AK Lindholm - BMC Evolutionary Biology, 2016 - Springer
Background With female multiple mating (polyandry), male-male competition extends to after
copulation (sperm competition). Males respond to this selective pressure through …

Testing a candidate meiotic drive locus identified by pool sequencing

DA Barbash, B Jin, KHC Wei… - G3: Genes, Genomes …, 2023 - academic.oup.com
Meiotic drive biases the transmission of alleles in heterozygous individuals, such that
Mendel's law of equal segregation is violated. Most examples of meiotic drive have been …

Unravelling the mystery of female meiotic drive: where we are

FE Clark, T Akera - Open Biology, 2021 - royalsocietypublishing.org
Female meiotic drive is the phenomenon where a selfish genetic element alters
chromosome segregation during female meiosis to segregate to the egg and transmit to the …

[HTML][HTML] New perspectives on the causes and consequences of male meiotic drive

C Courret, X Wei, AM Larracuente - Current Opinion in Genetics & …, 2023 - Elsevier
Gametogenesis is vulnerable to selfish genetic elements that bias their transmission to the
next generation by cheating meiosis. These so-called meiotic drivers are widespread in …

Genetic villains: killer meiotic drivers

MAB Núñez, NL Nuckolls, SE Zanders - Trends in genetics, 2018 - cell.com
Unbiased allele transmission into progeny is a fundamental genetic concept canonized as
Mendel's Law of Segregation. Not all alleles, however, abide by the law. Killer meiotic …

Meiotic drive of noncentromeric loci in mammalian meiosis II eggs

DMZA Silva, T Akera - Current Opinion in Genetics & Development, 2023 - Elsevier
Highlights•Selfish centromeres cheat only in female meiosis I.•Noncentromeric meiotic
drivers cheat more often in female meiosis II.•Cheating in female meiosis II can be …

Cell biology of cheating—transmission of centromeres and other selfish elements through asymmetric meiosis

L Chmátal, RM Schultz, BE Black… - … Discovering the Molecular …, 2017 - Springer
Abstract Mendel's First Law of Genetics states that a pair of alleles segregates randomly
during meiosis so that one copy of each is represented equally in gametes. Whereas male …