Meiotic drive in house mice: mechanisms, consequences, and insights for human biology
Meiotic drive occurs when one allele at a heterozygous site cheats its way into a
disproportionate share of functional gametes, violating Mendel's law of equal segregation …
disproportionate share of functional gametes, violating Mendel's law of equal segregation …
[HTML][HTML] When it comes to genetics, cheaters do prosper
SL Hanlon, AM Larracuente - Chromosome Research, 2022 - Springer
Though most genetic elements abide by these laws, others routinely break them to increase
their chances of being passed on to the next generation. This unlawful behavior by selfish …
their chances of being passed on to the next generation. This unlawful behavior by selfish …
Drive and sperm: the evolution and genetics of male meiotic drive
D Presgraves - Sperm biology, 2009 - Elsevier
Publisher Summary Some selfish genetic elements in eukaryotic genomes have been
harnessed to perform essential functions for their hosts, whereas others have gained …
harnessed to perform essential functions for their hosts, whereas others have gained …
[HTML][HTML] Meiotic drive changes sperm precedence patterns in house mice: potential for male alternative mating tactics?
A Sutter, AK Lindholm - BMC Evolutionary Biology, 2016 - Springer
Background With female multiple mating (polyandry), male-male competition extends to after
copulation (sperm competition). Males respond to this selective pressure through …
copulation (sperm competition). Males respond to this selective pressure through …
Testing a candidate meiotic drive locus identified by pool sequencing
DA Barbash, B Jin, KHC Wei… - G3: Genes, Genomes …, 2023 - academic.oup.com
Meiotic drive biases the transmission of alleles in heterozygous individuals, such that
Mendel's law of equal segregation is violated. Most examples of meiotic drive have been …
Mendel's law of equal segregation is violated. Most examples of meiotic drive have been …
Unravelling the mystery of female meiotic drive: where we are
FE Clark, T Akera - Open Biology, 2021 - royalsocietypublishing.org
Female meiotic drive is the phenomenon where a selfish genetic element alters
chromosome segregation during female meiosis to segregate to the egg and transmit to the …
chromosome segregation during female meiosis to segregate to the egg and transmit to the …
[HTML][HTML] New perspectives on the causes and consequences of male meiotic drive
Gametogenesis is vulnerable to selfish genetic elements that bias their transmission to the
next generation by cheating meiosis. These so-called meiotic drivers are widespread in …
next generation by cheating meiosis. These so-called meiotic drivers are widespread in …
Genetic villains: killer meiotic drivers
Unbiased allele transmission into progeny is a fundamental genetic concept canonized as
Mendel's Law of Segregation. Not all alleles, however, abide by the law. Killer meiotic …
Mendel's Law of Segregation. Not all alleles, however, abide by the law. Killer meiotic …
Meiotic drive of noncentromeric loci in mammalian meiosis II eggs
DMZA Silva, T Akera - Current Opinion in Genetics & Development, 2023 - Elsevier
Highlights•Selfish centromeres cheat only in female meiosis I.•Noncentromeric meiotic
drivers cheat more often in female meiosis II.•Cheating in female meiosis II can be …
drivers cheat more often in female meiosis II.•Cheating in female meiosis II can be …
Cell biology of cheating—transmission of centromeres and other selfish elements through asymmetric meiosis
Abstract Mendel's First Law of Genetics states that a pair of alleles segregates randomly
during meiosis so that one copy of each is represented equally in gametes. Whereas male …
during meiosis so that one copy of each is represented equally in gametes. Whereas male …