[HTML][HTML] Kaempferol derivatives as antiviral drugs against the 3a channel protein of coronavirus
The protein coded by the open-reading-frame 3a of SARS coronavirus has been
demonstrated to form a cation-selective channel that may become expressed in the infected …
demonstrated to form a cation-selective channel that may become expressed in the infected …
Emodin inhibits current through SARS-associated coronavirus 3a protein
S Schwarz, K Wang, W Yu, B Sun, W Schwarz - Antiviral research, 2011 - Elsevier
The open-reading-frame 3a of SARS coronavirus (SARS-CoV) had been demonstrated
previously to form a cation-selective channel that may become expressed in the infected cell …
previously to form a cation-selective channel that may become expressed in the infected cell …
The ion channel activity of the SARS-coronavirus 3a protein is linked to its pro-apoptotic function
The severe acute respiratory syndrome-coronavirus (SARS-CoV) caused an outbreak of
atypical pneumonia in 2003. The SARS-CoV viral genome encodes several proteins which …
atypical pneumonia in 2003. The SARS-CoV viral genome encodes several proteins which …
[HTML][HTML] Inhibition of SARS CoV envelope protein by flavonoids and classical viroporin inhibitors
U Breitinger, NKM Ali, H Sticht… - Frontiers in microbiology, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus (SARS-CoV), an enveloped single-stranded
positive-sense RNA virus, is a member of the genus Betacoronavirus, family Coronaviridae …
positive-sense RNA virus, is a member of the genus Betacoronavirus, family Coronaviridae …
Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release
W Lu, BJ Zheng, K Xu, W Schwarz… - Proceedings of the …, 2006 - National Acad Sciences
Fourteen ORFs have been identified in the severe acute respiratory syndrome-associated
coronavirus (SARS-CoV) genome. ORF 3a of SARS-CoV codes for a recently identified …
coronavirus (SARS-CoV) genome. ORF 3a of SARS-CoV codes for a recently identified …
Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction
Severe acute respiratory syndrome (SARS) is an emerging infectious disease caused by a
novel coronavirus (SARS-CoV). SARS-CoV spike (S) protein, a type I membrane-bound …
novel coronavirus (SARS-CoV). SARS-CoV spike (S) protein, a type I membrane-bound …
Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds
The 3C-like protease (3CLpro) of SARS-coronavirus mediates the proteolytic processing of
replicase polypeptides 1a and 1ab into functional proteins, becoming an important target for …
replicase polypeptides 1a and 1ab into functional proteins, becoming an important target for …
[HTML][HTML] Structure and inhibition of the SARS coronavirus envelope protein ion channel
K Pervushin, E Tan, K Parthasarathy, X Lin… - PLoS …, 2009 - journals.plos.org
The envelope (E) protein from coronaviruses is a small polypeptide that contains at least
one α-helical transmembrane domain. Absence, or inactivation, of E protein results in …
one α-helical transmembrane domain. Absence, or inactivation, of E protein results in …
Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells
L Yi, Z Li, K Yuan, X Qu, J Chen, G Wang… - Journal of …, 2004 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus (SARS-CoV) is the pathogen of SARS,
which caused a global panic in 2003. We describe here the screening of Chinese herbal …
which caused a global panic in 2003. We describe here the screening of Chinese herbal …
[HTML][HTML] Flavonoid-mediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris
TTH Nguyen, HJ Woo, HK Kang, VD Nguyen… - Biotechnology …, 2012 - Springer
Abstract The 3C-like protease (3CL pro) of severe acute respiratory syndrome associated
coronavirus (SARS-CoV) is vital for SARS-CoV replication and is a promising drug target …
coronavirus (SARS-CoV) is vital for SARS-CoV replication and is a promising drug target …