Characterization and antivirus activities of a novel bovine IFN-omega24

X Luo, Y Guo, J Bao, Y Liu, D An, B Ma, M Gao… - Molecular …, 2015 - Elsevier
A novel bovine interferon-ω (BoIFN-ω) gene, which encodes a protein of 195 amino acids
with a 23-amino acid signal peptide, was amplified from bovine liver genomic DNA through …

Design, biological activity and signaling pathway of bovine consensus omega interferon expressed in Pichia pastoris

M Gao, Y Guo, X Luo, J Du, Y Wang, C Cao… - Molecular …, 2019 - Elsevier
The bovine IFN-ω (BoIFN-ω) multigene family is located on chromosome 8, which has 14
potential functional genes and 10 pseudogenes. After aligning 14 BoIFN-ω subtypes and …

Characterization of the biological activities and physicochemical characteristics of recombinant bovine interferon-α14

J Shao, C Cao, J Bao, M Gao, J Wang - Molecular Immunology, 2015 - Elsevier
A BoIFN-α gene that included signal sequence was amplified from bovine liver genomic
DNA. The gene was named BoIFN-α 14 according to the position at which the encoded …

Molecular cloning and characterization of a novel bovine IFN-ε

Y Guo, M Gao, J Bao, X Luo, Y Liu, D An, H Zhang… - Gene, 2015 - Elsevier
A bovine IFN-ε (BoIFN-ε) gene was amplified from bovine liver genomic DNA consisting of a
463 bp partial 5′ UTR, 582 bp complete ORF and 171 bp partial 3′ UTR, which encodes a …

Molecular characterization and biological activity of bovine interferon-omega3

D An, Y Guo, J Bao, X Luo, Y Liu, B Ma, M Gao… - Research in veterinary …, 2017 - Elsevier
Abstract Bovine interferon-omega3 (BoIFN-ω3) gene was amplified from bovine liver
genomic DNA, which encodes a 195-amino acid protein containing a 23-amino acid signal …

[HTML][HTML] Analysis of the differential expression and antiviral activity of porcine interferon-α in vitro

J Fang, Q Zhang, Y Xi, L Lang, K Wang, S Li - International Journal of …, 2023 - Springer
Porcine interferon α (poIFN-α) is a crucial cytokine that can prevent and treat viral infections.
Seventeen functional porcine IFN-α subtypes were found in the porcine genome. In this …

[HTML][HTML] Biological Activity of Optimized Codon Bovine Type III Interferon Expressed in Pichia pastoris

R An, R Zhang, Y Guo, J Geng, M Si, S Wang, M Gao… - Viruses, 2023 - mdpi.com
Type III interferons (IFN–λs) exhibit potent antiviral activity and immunomodulatory effects in
specific cells. Nucleotide fragments of the bovine ifn–λ (boifn–λ) gene were synthetized after …

Identification and characterization of a rabbit novel IFN-α unlocated in genome

M Gao, Y Liu, Y Guo, Y Wang, H Dai, Z Song… - Developmental & …, 2018 - Elsevier
The multigene family of rabbit IFN-α (RbIFN-α) is located on chromosome 1, which shows
seven functional genes in type I IFN locus. A novel RbIFN-α that remains unlocated in the …

Characterization of Bovine Interferon α1: Expression in Yeast Pichia pastoris, Biological Activities, and Physicochemical Characteristics

J Shao, C Cao, J Bao, H Liu, T Peng… - Journal of Interferon & …, 2015 - liebertpub.com
A bovine interferon α (BoIFNα) gene that included signal sequence was amplified from
bovine liver genomic DNA. The gene was named BoIFN-α1 according to the position at …

Biological activity of recombinant bovine IFN-α and inhibitory effect on BVDV in vitro

H Yin, S Li, C Chai, F Zhang, Y Ma, Y Wu, C Fu… - Microbial …, 2023 - Elsevier
Type I interferon has great broad-spectrum antiviral ability and immunomodulatory function,
and its receptors are expressed in almost all types of cells. Bovine viral diarrhea virus …