Controlled degradation of chitosan-coated strontium-doped calcium sulfate hemihydrate composite cement promotes bone defect repair in osteoporosis rats

Q Miao, S Yang, H Ding, J Liu - Biomedical Materials, 2020 - iopscience.iop.org
Strontium (Sr)-doped calcium sulfate hemihydrate (SrCSH) bioactive materials have been
demonstrated to promote osteoporotic bone repair, being associated with the stimulation of …

Enhanced bone formation by strontium modified calcium sulfate hemihydrate in ovariectomized rat critical-size calvarial defects

S Yang, L Wang, S Feng, Q Yang, B Yu… - Biomedical …, 2017 - iopscience.iop.org
The development of a new generation of biomaterials with high osteogenic ability for
treatment of osteoporotic fractures is being intensively investigated. The objective of this …

Multi-stage controllable degradation of strontium-doped calcium sulfate hemihydrate-tricalcium phosphate microsphere composite as a substitute for osteoporotic …

Q Miao, N Jiang, Q Yang, IM Hussein, Z Luo… - Biomedical …, 2021 - iopscience.iop.org
Various requirements for the repair of complex bone defects have motivated to development
of scaffolds with adjustable degradation rates and biological functions. Tricalcium phosphate …

Strontium-substituted calcium sulfate hemihydrate/hydroxyapatite scaffold enhances bone regeneration by recruiting bone mesenchymal stromal cells

H Chang, H Xiang, Z Yao, S Yang… - Journal of …, 2020 - journals.sagepub.com
Fabrication of osteoconductive scaffold with osteoinductive capability and appropriate
resorption rate is of great significance for treating bone defects. To achieve this aim …

Novel bone substitute composed of chitosan and strontium-doped α-calcium sulfate hemihydrate: Fabrication, characterisation and evaluation of biocompatibility

Y Chen, Y Zhou, S Yang, JJ Li, X Li, Y Ma, Y Hou… - Materials Science and …, 2016 - Elsevier
Calcium sulfate is in routine clinical use as a bone substitute, offering the benefits of
biodegradability, biocompatibility and a long history of use in bone repair. The …

Improvement of in vitro physicochemical properties and osteogenic activity of calcium sulfate cement for bone repair by dicalcium silicate

CC Chen, CW Wang, NS Hsueh, SJ Ding - Journal of alloys and …, 2014 - Elsevier
An ideal bone graft substitute should have the same speed of degradation as formation of
new bone tissue. To improve the properties of calcium sulfate hemihydrate (CSH) featured …

Assessment of calcium sulfate hemihydrate–tricalcium silicate composite for bone healing in a rabbit femoral condyle model

F Hao, L Qin, J Liu, J Chang, Z Huan, L Wu - Materials Science and …, 2018 - Elsevier
Calcium sulfate or plaster of Paris (POP) is considered as a bone cement with a fast
degradation rate, which frequently makes it resorb before the bone defect area is completely …

Characterization of an α-calcium sulfate hemihydrates/α-tricalcium phosphate combined injectable bone cement

D Yang, Y Yan, X Liu, P Wang, G Huang… - ACS Applied Bio …, 2018 - ACS Publications
The artificial bone-repair materials have received extensive attention. In this study, we have
prepared new α-calcium sulfate hemihydrates (α-CSH) and gelatin modified α-tricalcium …

Promotion of in vivo degradability, vascularization and osteogenesis of calcium sulfate-based bone cements containing nanoporous lithium doping magnesium …

L Cao, W Weng, X Chen, J Zhang, Q Zhou… - International Journal …, 2017 - Taylor & Francis
Nanoporous lithium doping magnesium silicate (nl-MS) was introduced into calcium sulfate
hemihydrate to prepare calcium sulfate composite (nl-MSC) bone cements. The introduction …

A novel and injectable strontium-containing hydroxyapatite bone cement for bone substitution: A systematic evaluation

J Dai, Y Fu, D Chen, Z Sun - Materials Science and Engineering: C, 2021 - Elsevier
Reconstruction of bone defects is still a challenge. In this study, we developed and
systematically evaluated a novel injectable strontium-containing hydroxyapatite (Sr-HA) …