Mechanisms of severe cutaneous adverse reactions: recent advances

T Bellón - Drug safety, 2019 - Springer
Cutaneous adverse drug reactions are unpredictable and include various different skin
conditions of varying degrees of severity. The most concerning are usually referred to as …

Adverse cutaneous drug eruptions: current understanding

W Hoetzenecker, M Nägeli, ET Mehra… - Seminars in …, 2016 - Springer
Adverse cutaneous drug reactions are recognized as being major health problems
worldwide causing considerable costs for health care systems. Most adverse cutaneous …

Severe delayed cutaneous and systemic reactions to drugs: a global perspective on the science and art of current practice

JG Peter, R Lehloenya, S Dlamini, K Risma… - The Journal of Allergy …, 2017 - Elsevier
Most immune-mediated adverse drug reactions (IM-ADRs) involve the skin, and many have
additional systemic features. Severe cutaneous adverse drug reactions (SCARs) are an …

Recognition and management of severe cutaneous adverse drug reactions (including drug reaction with eosinophilia and systemic symptoms, Stevens-Johnson …

CE Owen, JM Jones - Medical Clinics, 2021 - medical.theclinics.com
Severe cutaneous adverse reactions to medications (SCARs) are dose-dependent
manifestations of hypersensitivity phenotypes. Drug reaction with eosinophilia and systemic …

Severe cutaneous adverse drug reactions: presentation, risk factors, and management

SS Mustafa, D Ostrov, D Yerly - Current allergy and asthma reports, 2018 - Springer
Abstract Purpose of Study Immune-mediated adverse drug reactions occur commonly in
clinical practice and include mild, self-limited cutaneous eruptions, IgE-mediated …

[HTML][HTML] Treatments for severe cutaneous adverse reactions

YT Cho, CY Chu - Journal of immunology research, 2017 - hindawi.com
Severe cutaneous adverse reaction (SCAR) is life-threatening. It consists of Stevens-
Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), drug reaction with eosinophilia …

[HTML][HTML] Drug-induced severe cutaneous adverse reactions: insights into clinical presentation, immunopathogenesis, diagnostic methods, treatment, and …

T Tempark, S John, P Rerknimitr… - Frontiers in …, 2022 - frontiersin.org
SCARs are rare and life-threatening hypersensitivity reactions. In general, the increased
duration of hospital stays and the associated cost burden are common issues, and in the …

An exploratory factor analysis of the spontaneous reporting of severe cutaneous adverse reactions

M Hauben, E Hung, WY Hsieh - Therapeutic advances in …, 2017 - journals.sagepub.com
Background: Severe cutaneous adverse reactions (SCARs) are prominent in
pharmacovigilance (PhV). They have some commonalities such as nonimmediate nature …

Recognition and management of severe cutaneous drug reactions

SR Knowles, NH Shear - Dermatologic clinics, 2007 - Elsevier
Cutaneous drug reactions are among the most common types of adverse drug reactions.
This article focuses on the recognition and management of severe cutaneous drug …

Severe cutaneous adverse drug reactions

WH Chung, CW Wang, RL Dao - The Journal of Dermatology, 2016 - Wiley Online Library
The clinical manifestations of drug eruptions can range from mild maculopapular exanthema
to severe cutaneous adverse drug reactions (SCAR), including drug‐induced …