The final common pathway of addiction (the dopamine hypothesis of reward) has recently
been evolving, with the mesocorticolimbic dopaminergic system now seen as key to natural …

Until recently, much of our knowledge of the neuropharmacology of addiction was derived
from animal studies, but we are now able to study the human brain directly and there is a …

Our knowledge about the neuropharmacology of addiction is increasing and is leading to
more informed development of pharmacotherapy. Although the dopaminergic mesolimbic …

The last decade brought a considerable progress in pharmacotherapy of addiction. Basing
on recently gained knowledge of mechanisms of development of addiction and the …

At the end of the decade of the brain, the study of neural mechanisms has come to dominate
the study of addiction. Whereas attention was once on somatic withdrawal symptoms and …

Addiction focuses on the emergence, nature, and persistence of addictive behavior, as well
as the efforts of addicts to overcome their condition. Do addicts act of their own free will, or …

This review gives an overview of what we see as the key issues in the human pharmacology
of drugs of addiction. We review evidence of efficacy and mechanisms by which treatments …

Piazza and Deroche-Gamonet have significantly contributed to the field of addiction and
published several pioneering articles that have had a major influence on the field. The latest …

Drug addiction is characterized by motivational disturbances such as compulsive drug
taking and episodes of intense drug craving. Recent advances using animal models of …

There is general consensus among preclinical researchers that dopamine plays an
important role in the development and persistence of addiction. However, the precise role of …