Purpose This paper concerns the cytotoxicity of 9-chloro-1-nitroacridine (1a) and 9-chloro-4-
methyl-1-nitroacridine (1b) against two biologically different melanoma forms: melanotic and …

Background: The lack of efficacious therapy for advanced melanoma and neuroblastoma
makes new approaches necessary. Therefore, many scientists seek new, more effective …

Acridines are a series of heterocyclic compounds, which have been received intense
interest and used as anti-inflammatory, antibacterial and antitumour agents. This paper …

Several acridine derivatives have been screened for their therapeutic potential and some
are already established as antiprotozoan, antibacterial or anticancer agents. However …

In this study, we show that triazoloacridinone derivative C-1305, a potent antitumor
compound, in human lymphoblastic (MOLT4) and promyelocytic (HL60) leukemia cells …

Background Acridine compounds have been described as promising anticancer agents.
Previous studies showed that (E)-1'-((4-chlorobenzylidene) amino)-5'-oxo-1', 5'-dihydro-10H …

Purpose As a continuation of our search for anticancer agents, we have synthesized a new
acridine-retrotuftsin analog HClx9-[Arg (NO 2)-Pro-Lys-Thr-OCH 3]-1-nitroacridine (named …

Synthesis of several new 9‐anilino, phenylhydrazino, and sulphonamido analogs of 2‐or 4‐
methoxy‐6‐nitroacridine derivatives is described. The prepared compounds were tested for …

Lung cancer is not only the most commonly diagnosed cancers worldwide but it is still the
leading cause of cancer-related death. Acridine derivatives are a class of anticancer agents …

Acridine derivatives show a broad range of biological activities. They have primarily been
explored as chemotherapeutic agents (anticancer, antibacterial, antiprotozoal), because of …