Quantification of Plasma 8-Isoprostane by High-Performance Liquid Chromatography with Tandem Mass Spectrometry in a Case-Control Study of Lung Cancer

L Ma, D Sun, G Xiu, P Lazarus, A Vachani… - International journal of …, 2022 - mdpi.com
Aim: 8-iso-prostaglandin F2α is a biomarker of lipid peroxidation, and one of the most
commonly used measures of oxidative stress. It is an established biomarker of lung cancer …

High-throughput and sensitive analysis of free and total 8-isoprostane in urine with isotope-dilution liquid chromatography-tandem mass spectrometry

C Holder, A Adams, E McGahee, B Xia, BC Blount… - ACS …, 2020 - ACS Publications
Oxidative stress (OS) plays a major role in the pathogenesis of various diseases in humans.
OS is a result of an imbalance between reactive oxygen species (ROS) and the biologically …

Urinary 8-isoprostane levels and occurrence of lung, colorectal, prostate, breast and overall cancer: results from a large, population-based cohort study with 14 years …

X Gào, H Brenner, B Holleczek, K Cuk, Y Zhang… - Free Radical Biology …, 2018 - Elsevier
Background Urinary 8‐isoprostane is an established biomarker for lipid peroxidation.
However, the association between its pre-diagnostic levels and cancer incidence has rarely …

8-Isoprostane as a marker of oxidative stress in nonsymptomatic cigarette smokers and COPD

VL Kinnula, H Ilumets, M Myllärniemi… - European …, 2007 - Eur Respiratory Soc
8-Isoprostane is a potential in vivo marker for oxidant burden, but its usefulness in induced
sputum of smokers and chronic obstructive pulmonary disease (COPD) has not been …

Rapid and sensitive quantification of 8-isoprostaglandin F2α in human plasma and urine by liquid chromatography–electrospray ionization mass spectrometry

N Ohashi, M Yoshikawa - … of Chromatography B: Biomedical Sciences and …, 2000 - Elsevier
The isoprostane, 8-isoprostaglandin F2α (8-iso-PGF2α), is produced non-enzymatically by
direct oxidation of arachidonic acid on the cell surface by oxygen radicals. We developed a …

HPLC–Atmospheric Pressure Chemical Ionization MS/MS for Quantification of 15-F2t-Isoprostane in Human Urine and Plasma

M Haschke, YL Zhang, C Kahle, J Klawitter… - Clinical …, 2007 - academic.oup.com
Abstract Background: Quantification of F2-Isoprostanes is considered a reliable index of the
oxidative stress status in vivo and is valuable in the diagnosis and monitoring of a variety of …

8-Isoprostane in exhaled breath condensate of patients with non-small cell lung cancer: the effect of chemotherapy

D Stathopoulos, S Loukides, K Syrigos - Anticancer Research, 2014 - ar.iiarjournals.org
Aim: The aim of the study was to evaluate the exhaled breath condensate (EBC) levels of a
valid oxidative stress marker, 8-isoprostane, before and after chemotherapy, in patients with …

Novel liquid chromatography method based on linear weighted regression for the fast determination of isoprostane isomers in plasma samples using sensitive tandem …

J Aszyk, J Kot, Y Tkachenko, M Woźniak… - … of Chromatography B, 2017 - Elsevier
A simple, fast, sensitive and accurate methodology based on a LLE followed by liquid
chromatography–tandem mass spectrometry for simultaneous determination of four …

Quantification of 15‐F2t‐isoprostane in human plasma and urine: results from enzyme‐linked immunoassay and liquid chromatography/tandem mass spectrometry …

J Klawitter, M Haschke, T Shokati… - Rapid …, 2011 - Wiley Online Library
Quantification of F2‐isoprostanes is considered a reliable index of the oxidative stress status
in vivo. Several immunoassays and chromatography/mass spectrometry‐based assays are …

Smoking and oxidant stress: assay of isoprostane in human urine by gas chromatography–mass spectrometry

T Obata, K Tomaru, T Nagakura, Y Izumi… - … of Chromatography B …, 2000 - Elsevier
Isoprostane (8-epi-prostaglandin F2a) is synthesized non-enzymatically from arachidonate
and active oxygen. We examined the relationship of smoking and excretion of isoprostane in …