Strategies for the design of orally bioavailable antileishmanial treatments

TTH Pham, PM Loiseau, G Barratt - International journal of pharmaceutics, 2013 - Elsevier
Leishmaniasis is one of the six major tropical diseases targeted by the World Health
Organization. The most serious, life-threatening form is visceral leishmaniasis (VL). No …

Recent advances in nanosystems and strategies for managing leishmaniasis

R Vaghela, PK Kulkarni, RAM Osmani… - Current drug …, 2017 - ingentaconnect.com
Background: Parasitic infection such as leishmaniasis, a neglected tropical disease,
presents a significant global burden which is responsible for high mortality rate especially in …

Drug delivery strategies for therapy of visceral leishmaniasis

S Gupta, A Pal, SP Vyas - Expert Opinion on Drug Delivery, 2010 - Taylor & Francis
Importance of the field: Visceral leishmaniasis (VL) is the most overwhelming type of
leishmaniasis associated with the poverty of developing countries and usually mortal if …

[HTML][HTML] Current status of nanoscale drug delivery and the future of nano-vaccine development for leishmaniasis–a review

P Prasanna, P Kumar, S Kumar, VK Rajana… - Biomedicine & …, 2021 - Elsevier
The study of tropical diseases like leishmaniasis, a parasitic disease, has not received much
attention even though it is the second-largest infectious disease after malaria. As per the …

Innovative solutions for the control of leishmaniases: nanoscale drug delivery systems

V Wagner, A Minguez-Menendez… - Current …, 2019 - ingentaconnect.com
Background: Leishmania are sandfly-transmitted protozoan parasites that harbour within the
macrophages of a mammalian host and cause leishmaniasis, a serious zoonotic disease …

Nanotechnology as an alternative to improve the treatment of cutaneous leishmaniasis: A systematic review of the literature

ES De Santana, VB de Souza Belmiro… - Journal of Drug Delivery …, 2022 - Elsevier
Cutaneous leishmaniasis (CL) is a neglected infectious disease caused by the Leishmania
spp parasite and transmitted through the bite of sandflies. Humans are infected by the …

Nanostructured delivery systems with improved leishmanicidal activity: a critical review

N Bruni, B Stella, L Giraudo, C Della Pepa… - International journal …, 2017 - Taylor & Francis
Leishmaniasis is a vector-borne zoonotic disease caused by protozoan parasites of the
genus Leishmania, which are responsible for numerous clinical manifestations, such as …

Promising nanotherapy in treating leishmaniasis

A de Souza, DSS Marins, SL Mathias… - International Journal of …, 2018 - Elsevier
Leishmaniases are infectious diseases caused by an intracellular protozoan in humans by
20 different species of Leishmania among more than 53 species. There are at least twelve …

Drug delivery systems against leishmaniasis? Still an open question

EL Romero, MJ Morilla - Expert opinion on drug delivery, 2008 - Taylor & Francis
Background: Leishmania amastigotes live inside resident macrophages in different
anatomic sites. Their hidden location is responsible for impairing the accession of …

Nanotechnological strategies for treatment of leishmaniasis—a review

L De Almeida, AT Fujimura, MLD Cistia… - Journal of …, 2017 - ingentaconnect.com
The World Health Organization (WHO) estimates that more than one billion people suffer
from neglected tropical diseases. Leishmaniasis is a widespread disease, affecting 12 …