B7-H4 overexpression impairs the immune response of T cells in human cervical carcinomas

X Wang, T Wang, M Xu, L Xiao, Y Luo, W Huang… - Human Immunology, 2014 - Elsevier
Abstract Objective To investigate B7-H4 expression and its correlation with the number of
infiltrating T lymphocytes and cytokine production by those lymphocytes in human cervical …

[HTML][HTML] Roles of B7-H3 in cervical cancer and its prognostic value

S Han, X Shi, L Liu, L Zong, J Zhang, Q Chen… - Journal of …, 2018 - ncbi.nlm.nih.gov
Abstract B7-H3, which has been reported to be a co-regulatory ligand of the B7 family, can
suppress T cell-mediated immunity and has also been reported to be expressed in many …

[HTML][HTML] B7-H3 promotes the proliferation, migration and invasiveness of cervical cancer cells and is an indicator of poor prognosis

Y Li, J Zhang, S Han, Q Qian, Q Chen… - Oncology …, 2017 - spandidos-publications.com
B7-H3 is an immune regulatory molecule whose aberrant expression in tumors is associated
with adverse outcomes. Upregulation of B7-H3 may promote tumor cell proliferation and …

Expression of B7-H3 in hypopharyngeal squamous cell carcinoma as a predictive indicator for tumor metastasis and prognosis

A Katayama, M Takahara… - International …, 2011 - spandidos-publications.com
B7-H3 is a member of the B7 family thought to be a co-regulatory factor of antigen-specific T-
cell immune response via co-stimulatory and co-inhibitory receptors. We evaluated its …

Tumor-expressed B7-H1 and B7-DC in relation to PD-1+ T-cell infiltration and survival of patients with cervical carcinoma

R Karim, ES Jordanova, SJ Piersma, GG Kenter… - Clinical Cancer …, 2009 - AACR
Purpose: The interaction between programmed cell death 1 (PD-1), expressed by activated
effector or regulatory T cells, and B7-H1 (PD-L1) and B7-DC (PD-L2) results in the inhibition …

B7-H4 expression in various tumors determined using a novel developed monoclonal antibody

Y Qian, L Shen, L Cheng, Z Wu, H Yao - Clinical and experimental …, 2011 - Springer
Abstract B7-H4, a new member of the B7 family, may participate in the negative regulation of
cell-mediated immunity, while aberrant B7-H4 expression is detected in some tumors and it …

B7-H4 expression promotes tumorigenesis in ovarian cancer

L Cheng, J Jiang, R Gao, S Wei, F Nan, S Li… - International Journal of …, 2009 - ijgc.bmj.com
Introduction: It has been previously shown that B7-H4, one of the B7 family members that
serve as negative regulators of T cell function, has altered expression levels in a variety of …

Epithelial and Tumor-associated Endothelial Expression of B7-H3 in Cervical Carcinoma: Relation With CD8:+: Intraepithelial Lymphocytes, FIGO Stage, and …

H Brustmann, M Igaz, C Eder… - International Journal of …, 2015 - journals.lww.com
B7-H3 is a transmembrane protein and a member of the B7 family of immune regulatory
ligands. It exerts both inhibitory and stimulatory effects on the activation of T cells. We …

Negative roles of B7-H3 and B7-H4 in the microenvironment of cervical cancer

S Han, Y Wang, X Shi, L Zong, L Liu, J Zhang… - Experimental cell …, 2018 - Elsevier
Although persistent human papilloma virus (HPV) infection exerts a crucial influence on
cervical carcinogenesis, other factors are also involved in its development, such as …

[HTML][HTML] Aberrant expression of B7-H3 in gastric adenocarcinoma promotes cancer cell metastasis Retraction in/10.3892/or. 2022.8421

W Dai, G Shen, J Qiu, X Zhao… - Oncology reports, 2014 - spandidos-publications.com
B7-H3 belongs to the B7 superfamily, a group of molecules that costimulate or
downmodulate T cell responses. Although it has been shown that B7-H3 can inhibit T cell …