Background Pulmonary surfactant dysfunction may contribute to the development of
ventilator induced lung injury (VILI). Tracheal gas insufflation (TGI) is a technique in which …

Objective To evaluate whether pulmonary surfactant (PS) impairment plays a role in the
development of ventilator-induced lung injury (VILI). Methods Thirty-two healthy adult …

Objective: It has been demonstrated that pulmonary surfactant plays a role in the
pathophysiology of ventilation-induced lung injury (VILI). Therefore, we investigated whether …

AIM: To evaluate the therapeutic efficacy of intratracheal instillation of porcine pulmonary
surfactant (PPS) in rats with lipopolysaccharides (LPS)-induced early-stage ALI in this study …

The development of acute respiratory distress syndrome (ARDS) is known to be
independently attributable to aspiration-induced lung injury. Mechanical ventilation as a …

Mechanical ventilation is an essential supportive therapy in the treatment of critical patients,
and it aims to maintain adequate gas exchange; however, it can also contribute to …

Objective: To compare intratracheal pulmonary ventilation (ITPV) with conventional
ventilation in a rabbit model of surfactant deficiency. Design: A prospective randomized …

Background: Overdistension of the lung causes ventilator‐induced lung injury (VILI)
accompanied by surfactant abnormalities and inflammatory changes. We investigated the …

Improvement of pulmonary perfusion and blood oxygenation and prevention of acute lung
injury (ALI) may rely on ventilation strategy. We hypothesized that application of a combined …

Objective To evaluate the effects of tracheal gas insufflation (TGI) on elimination of CO2 and
improvement of ventilation efficiency. Methods Using self-designed TGI device …